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患者旅行距离增加与复杂主动脉手术后围手术期和一年成本增加相关。

Greater Patient Travel Distance is Associated with Perioperative and One-Year Cost Increases After Complex Aortic Surgery.

机构信息

Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Boston, MA.

Department of Population Health Sciences, Weill Cornell Medicine, New York, NY.

出版信息

Ann Vasc Surg. 2023 Nov;97:289-301. doi: 10.1016/j.avsg.2023.05.040. Epub 2023 Jun 22.

Abstract

BACKGROUND

With increasing regionalization of complex aortic surgery within fewer US centers, patients may face increased travel burden when accessing aortic surgery. Longer travel distances have been associated with inferior outcomes after major surgery; however, the impacts of distance on reinterventions and costs have not been described. This study aims to assess the association between patient travel distance and longer-term outcomes including costs and reinterventions after complex aortic surgery.

METHODS

A retrospective review was conducted of all patients in the Vascular Implant Surveillance and Interventional Outcomes Network database undergoing complex endovascular aortic repair including internal iliac or visceral vessel involvement, complex thoracic endovascular aortic repair including Zone 0-2 proximal extent or branched devices, and complex open abdominal aortic aneurysm repair including suprarenal or higher clamp sites. Travel distance was stratified by Rural-Urban Commuting Area population-density category. Multinomial logistic regression models, negative-binomial models, and zero-inflated Poisson models were used to assess the association between travel distance and index procedural and comprehensive first-year costs, long-term imaging, and long-term reinterventions, respectively.

RESULTS

Between 2011 and 2018, 8,782 patients underwent complex aortic surgery in the Vascular Implant Surveillance and Interventional Outcomes Network database, including 4,822 complex endovascular aortic repairs, 2,672 complex thoracic endovascular aortic repairs, and 1,288 complex open abdominal aortic aneurysm repairs. Median travel distance was 22.8 miles (interquartile range 8.6-54.8 miles, range 0-2,688.9 miles). Median age was 75 years for all distance quintiles. Patients traveling farther were more likely to be female (26.8% in quintile 5 [Q5] vs. 19.9% in Q1, P < 0.001) and to have had a prior aortic surgery (20.8% for Q5 vs. 5.9% for Q1, P < 0.001). Patients traveling farther had higher index procedural costs, with adjusted odds ratio (OR) 2.34 (95% confidence interval [CI] 1.86-2.94, P < 0.0001) of being in the highest cost tertile versus lowest for patients in Q5 vs. Q1. For patients with ≥ 1-year follow-up, those traveling farther had higher imaging costs, with adjusted Q5 OR 1.55 (95% CI 1.22-1.95, P = 0.0002), and comprehensive first-year costs, with adjusted Q5 OR 2.06 (95% CI 1.57-2.70, P < 0.0001). In contrast, patients traveling farther had similar numbers of reinterventions and imaging studies postoperatively.

CONCLUSIONS

Patients traveling farther for complex aortic surgery have higher procedural costs, postoperative imaging costs, and comprehensive first-year costs. These patients should be targeted for increased care coordination for improved outcomes and healthcare system burden.

摘要

背景

随着复杂主动脉手术在美国少数中心的区域化程度不断提高,患者在接受主动脉手术时可能面临更大的旅行负担。较长的旅行距离与大手术后的预后不良有关;然而,距离对再干预和成本的影响尚未描述。本研究旨在评估患者旅行距离与包括成本和再干预在内的复杂主动脉手术后长期结果之间的关联。

方法

对血管植入物监测和介入结果网络数据库中所有接受复杂血管内主动脉修复术的患者进行回顾性分析,包括内脏或内部髂血管受累、复杂胸血管内主动脉修复术(包括 Z0-2 近端范围或分支装置)和复杂开放腹主动脉瘤修复术(包括肾上或更高的夹闭部位)。旅行距离按农村-城市通勤区人口密度类别分层。使用多项逻辑回归模型、负二项式模型和零膨胀泊松模型分别评估旅行距离与索引程序和综合第一年成本、长期影像学和长期再干预之间的关系。

结果

2011 年至 2018 年间,血管植入物监测和介入结果网络数据库中 8782 例患者接受了复杂主动脉手术,其中包括 4822 例复杂血管内主动脉修复术、2672 例复杂胸血管内主动脉修复术和 1288 例复杂开放腹主动脉瘤修复术。中位旅行距离为 22.8 英里(四分位距 8.6-54.8 英里,范围 0-2688.9 英里)。所有五分位组的中位年龄均为 75 岁。旅行距离较长的患者更有可能是女性(五分位组 26.8%,五分位组 19.9%,P<0.001),并且有过主动脉手术史(五分位组 20.8%,五分位组 5.9%,P<0.001)。旅行距离较长的患者指数程序成本更高,调整后的比值比(OR)为 2.34(95%置信区间 [CI] 1.86-2.94,P<0.0001),最高成本组(五分位组)与最低成本组(五分位组)相比,OR 为 2.34(95%置信区间 [CI] 1.86-2.94,P<0.0001)。对于有≥1 年随访的患者,与五分位组相比,旅行距离较远的患者术后影像学成本更高,调整后的五分位 OR 为 1.55(95%CI 1.22-1.95,P=0.0002),综合第一年成本更高,调整后的五分位 OR 为 2.06(95%CI 1.57-2.70,P<0.0001)。相比之下,旅行距离较远的患者术后再干预和影像学检查的数量相似。

结论

为复杂主动脉手术长途旅行的患者手术费用、术后影像学费用和综合第一年费用更高。这些患者应成为增加护理协调的目标,以改善预后和医疗系统负担。

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