Bloch Randall A, Brooks Ezra S, Nguyen Louis L
Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA.
Department of Surgery, Brigham and Women's Hospital, Boston, MA; Department of Surgery, Harvard Medical School, Boston, MA.
J Vasc Surg. 2025 Aug;82(2):665-672. doi: 10.1016/j.jvs.2025.03.483. Epub 2025 Apr 28.
Acute limb ischemia (ALI) results in high health care costs due to the near-universal need for surgical procedures and long hospital stays. Beyond the system costs incurred due to ALI, out-of-pocket (OOP) costs have a significant impact on patients' well-being and compliance with care. The objective of this study was to quantify OOP costs among individuals with ALI compared with the general population.
This was a cross-sectional study of individuals aged 18 years or older in the Agency for Healthcare Research and Quality Medical Expenditure Panel Survey (MEPS) from 2017 to 2021. The primary exposure was ALI, which was determined by MEPS clinical classification codes. The cohort of patients with ALI was compared against a population without pre-determined common and significant chronic comorbidities. The primary endpoints for comparison were adjusted OOP spending and rates of catastrophic health spending (CHS). Analyses were also conducted with the cohort stratified by income quartile.
A total of 2,172,062 weighted individuals with ALI were compared with 148,665,584 weighted individuals in the general population free of significant chronic disease. Individuals with ALI had significantly higher average annual OOP healthcare spending than the general population ($1992 vs $1013; β = 554.85; P = .001), which was driven by higher spending on inpatient hospitalizations ($140 vs $47; P < .001), prescription medications ($520 vs $158; P < .001), and other non-specified costs ($229 vs $48; P < .001). When stratifying by income quartile (low, lower-middle, upper-middle, and high income), the lower-middle income quartile (near-poor) had a CHS rate of 5.4%, compared with 0.1% to 1.1% in all other quartiles. Individuals with ALI had significantly higher rates of CHS in the lower-middle (13.9% vs 5.3%; P < .001) and upper-middle (3.1% vs 0.6%; P < .001) income quartiles, but not in the low (1.3% vs 1.0%; P = .719) or high (0.0% vs 0.1%; P = .695) income quartiles.
Individuals with ALI and near-poor individuals are especially vulnerable to high OOP health care spending. Efforts aimed at reducing hospital length of stay and reducing medication costs could reduce OOP spending among patients with ALI. Further, policy reform to expand insurance coverage among the near-poor group or implementation of means-based OOP spending limits could significantly mitigate the vulnerability of this group.
急性肢体缺血(ALI)因几乎普遍需要外科手术和长时间住院,导致医疗成本高昂。除了ALI造成的系统成本外,自付费用(OOP)对患者的福祉和治疗依从性有重大影响。本研究的目的是量化ALI患者与普通人群相比的自付费用。
这是一项对2017年至2021年医疗保健研究与质量机构医疗支出面板调查(MEPS)中18岁及以上个体的横断面研究。主要暴露因素是ALI,由MEPS临床分类代码确定。将ALI患者队列与没有预先确定的常见和重大慢性合并症的人群进行比较。比较的主要终点是调整后的自付支出和灾难性医疗支出(CHS)率。还对按收入四分位数分层的队列进行了分析。
总共2172062名加权的ALI患者与148665584名无重大慢性病的普通人群加权个体进行了比较。ALI患者的平均年度自付医疗支出显著高于普通人群(1992美元对1013美元;β = 554.85;P = 0.001),这是由住院费用(140美元对47美元;P < 0.001)、处方药费用(520美元对158美元;P < 0.001)和其他未指定费用(229美元对48美元;P < 0.001)的较高支出驱动的。按收入四分位数(低、中低、中高和高收入)分层时,中低收入四分位数(接近贫困)的CHS率为5.4%,而其他所有四分位数为0.1%至1.1%。ALI患者在中低收入(13.9%对5.3%;P < 0.001)和中高收入(3.1%对0.6%;P < 0.001)四分位数中的CHS率显著更高,但在低收入(1.3%对1.0%;P = 0.719)或高收入(0.0%对0.1%;P = 0.695)四分位数中并非如此。
ALI患者和接近贫困的个体特别容易受到高额自付医疗支出的影响。旨在缩短住院时间和降低药物成本的努力可以减少ALI患者的自付支出。此外,扩大接近贫困群体保险覆盖范围的政策改革或实施基于收入的自付支出限制可以显著减轻该群体的脆弱性。