Kendall Jamil S, Forlenza Enrico M, Shinn Daniel, DeBenedetti Anne, Yadav Aditya, Sporer Scott M
Parkview Orthopaedic Group, Palos Heights, Illinois, USA.
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA.
Bone Jt Open. 2025 May 1;6(5 Supple A):51-56. doi: 10.1302/2633-1462.65.BJO-2024-0239.R1.
Intra-articular (IA) injections are a useful diagnostic tool in patients presenting with debilitating hip pain but radiologically mild osteoarthritis (OA). We aim to explore the clinical and patient-reported outcomes (PROs) associated with patients who have radiologically mild OA and undergo total hip arthroplasty (THA) after an IA injection.
Patients undergoing primary, elective THA at a single centre between January 2017 and December 2023 were identified. Only those patients who underwent an IA injection into the operative hip within one year of surgery were included. Patients were divided into two cohorts based on the severity of their OA: those with Kellgren-Lawrence (KL) grade I to II arthritis were classified as 'mild', whereas those with KL grade III to IV arthritis were classified as 'severe'. Clinical outcomes and PROs, including the Hip disability and Osteoarthritis Outcome score for Joint Replacement, the Harris Hip Score, Single Assessment Numeric Evaluation, and Veterans Rand 12-Item Health Survey Mental and Physical subscales were compared between cohorts.
The final cohorts included 25 and 225 patients with radiologically mild and severe OA, respectively. There were no baseline differences in age, sex, or time between IA injection and THA between cohorts. There were no significant differences in the preoperative or postoperative PRO values between patients with mild or severe arthritis (all p > 0.05). There were no significant differences in the change in PRO scores from the preoperative to final follow-up, or the percentage of patients who achieved the minimal clinically important difference on any of the PROs between cohorts. There were also no significant differences in the studied complications between groups.
Patients with radiologically mild OA who feel relief of their hip pain following an IA injection report similar preoperative debility and postoperative improvements in PROs following THA compared with patients with radiologically severe OA.
对于出现髋关节疼痛但影像学表现为轻度骨关节炎(OA)的患者,关节内(IA)注射是一种有用的诊断工具。我们旨在探讨影像学表现为轻度OA且在IA注射后接受全髋关节置换术(THA)的患者的临床和患者报告结局(PROs)。
确定2017年1月至2023年12月在单一中心接受初次择期THA的患者。仅纳入在手术一年内对手术髋关节进行IA注射的患者。根据OA严重程度将患者分为两个队列:Kellgren-Lawrence(KL)分级为I至II级关节炎的患者被分类为“轻度”,而KL分级为III至IV级关节炎的患者被分类为“重度”。比较队列之间的临床结局和PROs,包括关节置换的髋关节功能障碍和骨关节炎结局评分、Harris髋关节评分、单评估数字评价以及退伍军人兰德12项健康调查的心理和身体分量表。
最终队列分别包括25例和225例影像学表现为轻度和重度OA的患者。队列之间在年龄、性别或IA注射与THA之间的时间方面没有基线差异。轻度或重度关节炎患者术前或术后的PRO值没有显著差异(所有p>0.05)。从术前到最终随访的PRO评分变化,或在任何PRO上达到最小临床重要差异的患者百分比在队列之间没有显著差异。两组之间研究的并发症也没有显著差异。
与影像学表现为重度OA的患者相比,影像学表现为轻度OA且在IA注射后髋关节疼痛缓解的患者在THA术前报告类似的功能障碍,术后PROs改善情况也相似。