Department of General Practice, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Department of General Practice, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Ann Rheum Dis. 2021 Apr;80(4):487-493. doi: 10.1136/annrheumdis-2020-218625. Epub 2021 Jan 15.
To explore the natural course of hip osteoarthritis (OA) in a population of first-time presenters with hip complaints.
Data were collected at baseline and after 2, 5, 8 and 10 years on participants from the Cohort Hip and Cohort Knee study with early symptomatic hip OA. Descriptive statistics were used to analyse the natural course of the hip complaints with respect to clinical signs and symptoms, physical functioning and radiographic osteoarthritis (ROA) features.
In total, 588 participants were included with hip complaints and 86% completed the 10-year follow-up. The 10-year follow-up showed that 12% (69 participants) underwent hip replacement (HR), an increase of ROA of the hip (Kellgren and Lawrence score≥2) from 19% to 49%, and an increase in clinical hip OA according to the American College of Rheumatology criteria from 27% to 43%. All Western Ontario and McMaster Osteoarthritis Index subscales and physical activity remained on average constant during the 10-year follow-up for those who did not undergo an HR. The use of pain medication increased from 43% at baseline to 50% after 10 years.
One out of nine participants with early hip problems received an HR during the 10-year follow-up. Prevalence of clinical hip OA and hip ROA increased steadily during the 10-year follow-up. Overall, we observed more hip OA, but fewer or stable complaints with respect to clinical signs and symptoms, and physical functioning. So it could be cautiously concluded that after 10 years, first-time presenters with hip complaints either received an HR or their symptoms remained stable.
探讨首次出现髋部症状的人群中髋骨关节炎（OA）的自然病程。
本研究的数据来源于髋骨队列研究和膝骨队列研究的初次出现髋部症状的早期症状性髋 OA 患者，在基线时以及 2、5、8 和 10 年时进行收集。采用描述性统计方法分析髋部症状的自然病程与临床体征和症状、身体功能以及放射学骨关节炎（ROA）特征的关系。
共纳入 588 名髋部有症状的患者，其中 86%完成了 10 年随访。10 年随访显示，12%（69 名患者）接受了髋关节置换（HR），髋关节 ROA（Kellgren 和 Lawrence 评分≥2）从 19%增加到 49%，美国风湿病学会标准下的临床髋 OA 从 27%增加到 43%。在未接受 HR 的患者中，所有 Western Ontario 和 McMaster Osteoarthritis Index 亚量表和体力活动在 10 年随访期间平均保持不变。从基线时的 43%增加到 10 年后的 50%。
在 10 年随访期间，9 名初次出现髋部问题的患者中有 1 名接受了 HR。在 10 年随访期间，临床髋 OA 和髋关节 ROA 的患病率稳步上升。总的来说，我们观察到更多的髋 OA，但在临床体征和症状以及身体功能方面，髋部的 OA 或症状较少或保持稳定。因此，可以谨慎地得出结论，在 10 年后，初次出现髋部症状的患者要么接受了 HR，要么他们的症状保持稳定。
