Rodriguez-Martín Minerva, González-Aguado Rocío, Sotos Trinidad Dierssen, Morales-Angulo Carmelo
Department of Otolaryngology, Marqués de Valdecilla University Hospital, Santander, Cantabria, Spain.
Otol Neurotol. 2025 Jul 1;46(6):680-685. doi: 10.1097/MAO.0000000000004508. Epub 2025 Apr 22.
This study aims to determine the percentage of patients with idiopathic sudden hearing loss later diagnosed with Ménière's disease. It also seeks to identify predictive factors for Ménière's diagnosis and compare treatment responses between first-time Ménière's patients and those with idiopathic sudden hearing loss.
A prospective observational study.
Tertiary referral center.
Cohort of apparently idiopathic sudden hearing loss patients over a period of 30 years (1992-2022).
Identification of Ménière's disease cases during follow-up.
Determining how many were subsequently diagnosed with definitive Ménière's disease.
From a cohort of 369 patients with apparently idiopathic sudden hearing loss treated over 30 years, 15 (4%) developed definite Ménière's disease.The predictive factors for developing Ménière's disease were mild to moderate hearing loss, vertigo, tinnitus at the initial episode, and a predominantly ascending audiometric curve.When comparing treatment responses, patients with Ménière's disease showed better outcomes than those with idiopathic sudden hearing loss.
Cases of sudden sensorineural hearing loss that represent the first episode of definite Ménière's disease are rare. A moderate hearing loss at low frequencies, accompanied by tinnitus and vertigo during an episode of sudden hearing loss, should raise suspicion for Ménière's disease rather than idiopathic sudden hearing loss. Patients with sudden hearing loss secondary to an episode of Ménière's disease tend to show significantly greater hearing improvement compared with those with idiopathic sudden hearing loss.
本研究旨在确定特发性突聋患者中后来被诊断为梅尼埃病的比例。它还试图确定梅尼埃病诊断的预测因素，并比较初发性梅尼埃病患者与特发性突聋患者的治疗反应。
一项前瞻性观察性研究。
三级转诊中心。
30年（1992 - 2022年）期间明显为特发性突聋患者队列。
随访期间识别梅尼埃病病例。
确定随后被确诊为明确梅尼埃病的患者数量。
在30年中接受治疗的369例明显特发性突聋患者队列中，15例（4%）发展为明确的梅尼埃病。发展为梅尼埃病的预测因素为轻度至中度听力损失、眩晕、初次发作时耳鸣以及主要为上升型听力曲线。比较治疗反应时，梅尼埃病患者的结局比特发性突聋患者更好。
代表明确梅尼埃病首发发作的突发性感音神经性听力损失病例很少见。低频中度听力损失，伴有突发性听力损失发作期间的耳鸣和眩晕，应怀疑为梅尼埃病而非特发性突聋。与特发性突聋患者相比，梅尼埃病发作继发的突聋患者听力改善往往明显更大。
