Suppr超能文献

非心脏手术成年患者的术中血流动力学监测与管理:欧洲麻醉学与重症监护学会声明

Intra-operative haemodynamic monitoring and management of adults having noncardiac surgery: A statement from the European Society of Anaesthesiology and Intensive Care.

作者信息

Saugel Bernd, Buhre Wolfgang, Chew Michelle S, Cholley Bernard, Coburn Mark, Cohen Barak, De Hert Stefan, Duranteau Jacques, Fellahi Jean-Luc, Flick Moritz, Guarracino Fabio, Joosten Alexandre, Jungwirth Bettina, Kouz Karim, Longrois Dan, Buse Giovanna Lurati, Meidert Agnes S, Rex Steffen, Romagnoli Stefano, Romero Carolina S, Sander Michael, Thomsen Kristen K, Vos Jaap Jan, Zarbock Alexander

机构信息

From the Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (BS, MF, KK, KKT), the Outcomes Research Consortium, Houston, Texas, USA (BS, BCo, KK, KKT), the Department of Anesthesiology, Division of Vital Functions, University Medical Centre Utrecht, Utrecht, The Netherlands (WB), the Department of Perioperative Medicine and Intensive Care, Karolinska University Hospital Huddinge, Huddinge, Sweden (MSC), the Department of Anesthesiology and Intensive Care Medicine, Hôpital européen Georges-Pompidou, Assistance Publique-Hôpitaux de Paris and Université Paris Cité, Paris, France (BCh), the Department of Anaesthesiology and Operative Intensive Care Medicine, University Hospital Bonn, Bonn, Germany (MC), the Division of Anesthesia, Intensive Care, and Pain, Tel-Aviv Medical Center, Tel-Aviv University, Tel-Aviv, Israel (BCo), the Department of Basic and Applied Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium (SDH), the Department of Anesthesiology and Intensive Care, Paris-Saclay University, Bicêtre Hospital, Assistance Publique-Hôpitaux de Paris, Le Kremlin-Bicêtre, France (JD), the Department of Cardiothoracic and Vascular Anaesthesia and Intensive Care, Louis Pradel University Hospital, Hospices Civils de Lyon, Bron, France (JLF), the Department of Cardiothoracic and Vascular Anaesthesia and Intensive Care, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy (FG), the Department of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine at UCLA, University of California Los Angeles, California, USA (AJ), the Department of Anaesthesiology and Intensive Care Medicine, University Hospital Ulm, Ulm, Germany (BJ), the Department of Anaesthesia and Intensive Care, Bichat-Claude Bernard and Louis Mourier Hospitals, Assistance Publique-Hôpitaux de Paris, Paris, France (DL), the Department of Anesthesiology, University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, Duesseldorf, Germany (GLB), the Department of Anaesthesiology, University Hospital LMU Munich, Munich, Germany (ASM), the Department of Anesthesiology, University Hospitals Leuven, Leuven, Belgium (SRe), the Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium (SRe), the Department of Health Science, University of Florence, Florence, Italy (SRo), the Department of Anesthesia and Critical Care, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy (SRo), the Department of Anaesthesiology and Critical Care, Hospital General Universitario de Valencia, Valencia, Spain (CSR), the Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Giessen, Justus-Liebig-University, Giessen, Germany (MS), the Department of Anesthesiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands (JJV), the Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Muenster, Muenster, Germany (AZ).

出版信息

Eur J Anaesthesiol. 2025 Jun 1;42(6):543-556. doi: 10.1097/EJA.0000000000002174. Epub 2025 May 7.

Abstract

This article was developed by a diverse group of 25 international experts from the European Society of Anaesthesiology and Intensive Care (ESAIC), who formulated recommendations on intra-operative haemodynamic monitoring and management of adults having noncardiac surgery based on a review of the current evidence. We recommend basing intra-operative arterial pressure management on mean arterial pressure and keeping intra-operative mean arterial pressure above 60 mmHg. We further recommend identifying the underlying causes of intra-operative hypotension and addressing them appropriately. We suggest pragmatically treating bradycardia or tachycardia when it leads to profound hypotension or likely results in reduced cardiac output, oxygen delivery or organ perfusion. We suggest monitoring stroke volume or cardiac output in patients with high baseline risk for complications or in patients having high-risk surgery to assess the haemodynamic status and the haemodynamic response to therapeutic interventions. However, we recommend not routinely maximising stroke volume or cardiac output in patients having noncardiac surgery. Instead, we suggest defining stroke volume and cardiac output targets individually for each patient considering the clinical situation and clinical and metabolic signs of tissue perfusion and oxygenation. We recommend not giving fluids simply because a patient is fluid responsive but only if there are clinical or metabolic signs of hypovolaemia or tissue hypoperfusion. We suggest monitoring and optimising the depth of anaesthesia to titrate doses of anaesthetic drugs and reduce their side effects.

摘要

本文由来自欧洲麻醉与重症监护学会(ESAIC)的25位不同领域的国际专家共同撰写,他们在回顾当前证据的基础上,针对非心脏手术成年患者的术中血流动力学监测与管理制定了建议。我们建议基于平均动脉压进行术中动脉压管理,并使术中平均动脉压保持在60 mmHg以上。我们还建议识别术中低血压的潜在原因并进行适当处理。当心动过缓或心动过速导致严重低血压或可能导致心输出量、氧输送或器官灌注减少时,我们建议采取务实的治疗措施。对于并发症基线风险高的患者或进行高风险手术的患者,我们建议监测每搏量或心输出量,以评估血流动力学状态以及对治疗干预的血流动力学反应。然而,对于接受非心脏手术的患者,我们建议不要常规地将每搏量或心输出量最大化。相反,我们建议根据每位患者的临床情况以及组织灌注和氧合的临床和代谢体征,为其分别确定每搏量和心输出量目标。我们建议不要仅仅因为患者对液体有反应就给予液体,而仅在存在低血容量或组织灌注不足的临床或代谢体征时才给予。我们建议监测并优化麻醉深度,以调整麻醉药物剂量并减少其副作用。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验