Yang Yu-Hang, Zhang Yue-Ming, Liu An-Hao, Luo Guang-Cheng, Liu Zheng-Jin, Xie Jian-Wei
Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Department of Urology, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Front Oncol. 2025 Apr 16;15:1543068. doi: 10.3389/fonc.2025.1543068. eCollection 2025.
The perinephric myxoid pseudotumor of fat (PMPF) is an uncommon benign neoplasm characterized by a favorable prognosis. To date, 21 cases of PMPFs have been reported worldwide, and their detailed characteristics have not been fully elucidated. We report the 22nd case of PMPF, which is the first case in China and happened in a 54-year-old male with a 5.6 cm mass located in the lower inner aspect of the right kidney. The patient underwent a minimally invasive robot-assisted laparoscopic resection of the renal mass. Postoperative histopathological, immunohistochemical, and genetic testing results confirmed the diagnosis of PMPF. No evidence of recurrence was found during a follow-up period of 6 months postoperatively based on clinical and imaging data. This is a report of an unusual case of PMPF with an up-to-date review. According to the latest systematic review and clinical confirmation, PMPF is strongly associated with chronic kidney disease, which is further confirmed by our case. For PMPF, combining imaging methods and immunohistochemical staining is suggested, which may prove beneficial in clinical practice.
肾周脂肪黏液样假瘤（PMPF）是一种罕见的良性肿瘤，预后良好。迄今为止，全球已报道21例PMPF，其详细特征尚未完全阐明。我们报告第22例PMPF，这是中国首例，发生在一名54岁男性身上，右肾内下侧有一个5.6厘米的肿块。患者接受了机器人辅助腹腔镜微创肾肿块切除术。术后组织病理学、免疫组织化学和基因检测结果证实了PMPF的诊断。根据临床和影像学数据，术后6个月的随访期间未发现复发迹象。这是一篇关于PMPF罕见病例的报告及最新综述。根据最新的系统综述和临床证实，PMPF与慢性肾病密切相关，我们的病例进一步证实了这一点。对于PMPF，建议结合影像学方法和免疫组织化学染色，这在临床实践中可能证明是有益的。
