Zhang Fenxiang, Liu Yujin
Department of Interventional Oncology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Front Oncol. 2025 Apr 16;15:1551644. doi: 10.3389/fonc.2025.1551644. eCollection 2025.
Transcatheter arterial chemoembolization may enhance the local concentration and cytotoxicity of chemotherapeutic drugs and block the blood supply to the tumor, with an expectation to control the tumor, relieve hemoptysis, and prolong survival. This review will introduce the research progression of blood supply to lung cancer, discuss pulmonary artery chemoembolization (PACE) and bronchial artery chemoembolization (BACE) for lung cancer, including their indications and contraindications, operation techniques, efficacy assessments, combined treatments as well as their operating complications and the methods to prevent the adverse event. We will discuss the problems and challenges of percutaneous vascular intervention for lung cancer, such as the uncertainty of blood supply artery for lung cancer, the necessity of high-quality controlled studies, and the best choice for the indications. We hope to explore the direction of transcatheter arterial chemoembolization for lung cancer. The aim of this review is to provide a reference for the practice of chemoembolization by vascular interventional radiology for lung cancer.
经导管动脉化疗栓塞术可提高化疗药物的局部浓度和细胞毒性，并阻断肿瘤的血供，有望控制肿瘤、缓解咯血及延长生存期。本文将介绍肺癌血供的研究进展，探讨肺癌的肺动脉化疗栓塞术（PACE）和支气管动脉化疗栓塞术（BACE），包括其适应证和禁忌证、操作技术、疗效评估、联合治疗以及手术并发症和不良事件的预防方法。我们将讨论肺癌经皮血管介入治疗存在的问题与挑战，如肺癌供血动脉的不确定性、高质量对照研究的必要性以及适应证的最佳选择。我们希望探索肺癌经导管动脉化疗栓塞术的发展方向。本文旨在为肺癌血管介入放射学化疗栓塞术的实践提供参考。
