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英国单中心使用新型机器人尺蠖式结肠镜检查系统的试点经验。

A UK single-center pilot experience using a novel robotic inchworm colonoscopy system.

作者信息

Ahmed Jabed F, Coda Sergio, Premchand Purushothaman, Banerjee Saswata, Patel Nisha

机构信息

The Hamlyn Center Imperial College London London UK.

Gastroenterology Imperial College Healthcare NHS Trust London UK.

出版信息

DEN Open. 2025 Apr 29;6(1):e70123. doi: 10.1002/deo2.70123. eCollection 2026 Apr.

Abstract

INTRODUCTION

Colonoscopy is the gold standard investigation in the lower gastrointestinal tract. However, 75% of patients can experience pain with moderate sedation. The application of robotic technology aims to overcome difficulties faced including better utilization of rooms for advanced procedures and to achieve a complete colonoscopy in patients restricted by pain and technical challenges.

METHODS

This pilot study, the first at a UK-National Health Service Hospital between January 2023 to August 2024 with one expert endoscopist performing the robotic colonoscopy (RC). Patients with failed previous standard colonoscopy (SC) along with index diagnostic procedures deemed potentially difficult were recruited. Procedures were performed outside the endoscopy unit similar to an outpatient clinical room.

RESULTS

Ninety-three patients were recruited (41 men:52 women), mean age of 53.8 years over 20 months. The commonest indications for RC were rectal bleeding (26.9%), failed SC (22.6%), and change in bowel habits (17.2%). Twenty-one patients had failed the previous SC with 14 patients achieving completion with subsequent RC (66% improvement). The average cecal intubation time of 41.07 min with an average total procedure time of 76.48 min. A significant improvement in patient discomfort score was reported (4.71 SC vs. 1.71 RC;  < 0.001).

CONCLUSIONS

RC provides a significantly more comfortable colonoscopy and has great potential to improve safety in colonoscopy from this early cohort of patients. Direct visualization, biopsy, and polypectomy are still possible with RC. This study has demonstrated a viable alternative to SC. With no sedation it allows procedures to be conducted outside the traditional endoscopy unit such as outpatients. The study highlights a learning curve to reduce cecal intubation time.

摘要

引言

结肠镜检查是下消化道检查的金标准。然而,75%的患者在适度镇静下会感到疼痛。机器人技术的应用旨在克服所面临的困难,包括更好地利用空间进行高级手术,并在因疼痛和技术挑战而受限的患者中完成全结肠镜检查。

方法

这项前瞻性研究是2023年1月至2024年8月在英国国民健康服务医院进行的首例研究,由一名专家内镜医师进行机器人结肠镜检查(RC)。招募了先前标准结肠镜检查(SC)失败的患者以及被认为可能困难的索引诊断程序患者。手术在类似于门诊临床室的内镜单元外进行。

结果

在20个月内招募了93名患者(41名男性:52名女性),平均年龄53.8岁。RC最常见的适应证是直肠出血(26.9%)、SC失败(22.6%)和排便习惯改变(17.2%)。21名患者先前的SC失败,其中14名患者随后通过RC完成检查(改善率66%)。平均盲肠插管时间为41.07分钟,平均总手术时间为76.48分钟。据报告患者不适评分有显著改善(SC为4.71分,RC为1.71分;<0.001)。

结论

RC提供了明显更舒适的结肠镜检查,并且从这一早期患者队列来看,在提高结肠镜检查安全性方面具有巨大潜力。RC仍然可以进行直接可视化、活检和息肉切除术。这项研究证明了SC的一种可行替代方案。无需镇静,它允许在传统内镜单元之外(如门诊)进行手术。该研究突出了减少盲肠插管时间的学习曲线。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f4c/12038173/1e1e4851afb1/DEO2-6-e70123-g003.jpg

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