Tinh Do Xuan, Hung Dinh Viet, Thuan Do Duc, Duc Dang Phuc, Duc Dang Minh, Cuong Nguyen Dang, Ha Phan The, Hai Nguyen Dang, Thuan Nguyen Duc, Tuan Tran Minh, Lang Huynh Ngoc, Nghia Nguyen Trong, Thao Pham Ngoc
Department of Psychiatry, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam.
Department of Stroke, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam.
SAGE Open Med. 2025 Apr 29;13:20503121251336900. doi: 10.1177/20503121251336900. eCollection 2025.
The incidence of stroke-related restless legs syndrome (RLS) has been reported to be high but varies regionally. Therefore, this study aimed to investigate the incidence and some of the factors related to restless legs syndrome after stroke onset in patients in Vietnam.
Data were collected from a total of 423 patients who had stroke, including 283 ischemic and 140 hemorrhagic strokes, which were confirmed by magnetic resonance imaging within 7 days after the onset of symptoms, at the Department of Stroke, Military Hospital 103 from September 2023 to April 2024. Restless legs syndrome was diagnosed 1 month after the stroke onset according to the criteria of the International Restless Legs Syndrome Study Group.
Restless legs syndrome was diagnosed in 59 patients (11.6%), including 37 (13.1%) who had ischemic stroke and 12 (8.6%) who had hemorrhagic stroke. An increased rate of restless legs syndrome was observed in stroke patients with brain lesions in the thalamus and lentiform nucleus; those who smoked; and those with a family history of restless legs syndrome.
This study found that the incidence of restless legs syndrome after stroke was 11.6% overall and 13.1% and 8.6% after ischemic and hemorrhagic strokes, respectively. Lesion in the thalamus and lentiform nucleus, smoking history, and family history of restless legs syndrome were the predictors of restless legs syndrome after stroke onset.
据报道,与中风相关的不安腿综合征(RLS)发病率较高,但存在地区差异。因此,本研究旨在调查越南患者中风发作后不安腿综合征的发病率及一些相关因素。
收集了2023年9月至2024年4月期间在103军事医院中风科就诊的423例中风患者的数据,其中包括283例缺血性中风和140例出血性中风,均在症状发作后7天内通过磁共振成像确诊。根据国际不安腿综合征研究组的标准,在中风发作1个月后诊断不安腿综合征。
59例患者(11.6%)被诊断为不安腿综合征,其中缺血性中风患者37例(13.1%),出血性中风患者12例(8.6%)。在丘脑和豆状核有脑损伤的中风患者、吸烟患者以及有不安腿综合征家族史的患者中,不安腿综合征的发生率增加。
本研究发现,中风后不安腿综合征的总体发病率为11.6%,缺血性中风和出血性中风后分别为13.1%和8.6%。丘脑和豆状核损伤、吸烟史以及不安腿综合征家族史是中风发作后不安腿综合征的预测因素。