Fu Wei, Bai Ya, Wang Xiaoming
Department of Geriatrics, Xijing Hospital, Air Force Medical University, Xi'an, China.
Department of Neurology, Xijing Hospital, Air Force Medical University, Xi'an, China.
Front Neurosci. 2025 Apr 16;19:1580078. doi: 10.3389/fnins.2025.1580078. eCollection 2025.
Galvanic vestibular stimulation (GVS) may potentially improve postural rehabilitation. However, the postural control role of GVS in the neurological disorders has not been systematically reviewed.
We conducted a systematic review on PubMed, EMBASE, and Web of Science to synthesize key findings of the effectiveness of single and multiple sessions of GVS alone and combined with other interventions on balance in adults with neurological disorders. Diagnosis of neurological disorders, sample size, age and gender of participants, GVS parameters, postural assessments, and study findings were extracted following the PRISMA guidelines. Newcastle-Ottawa scale was used to assess study quality.
Twenty-five studies were included in the systematic review. Clinical application of GVS for postural control included Parkinson's disease, bilateral vestibulopathy, stroke-induced hemiplegia, multiple sclerosis, progressive supranuclear palsy, persistent postural-perceptual dizziness, and unilateral vestibulopathy. GVS effectively improves postural control in most neurological disorders. Risk of bias assessment showed that most studies had a low risk of bias.
GVS is a promising complementary therapy to improve postural control and balance in adults with neurological disorders. Future high quality studies should be performed to confirm these findings.
直流电前庭刺激（GVS）可能会改善姿势康复。然而，GVS在神经系统疾病中对姿势控制的作用尚未得到系统评价。
我们在PubMed、EMBASE和科学网上进行了一项系统评价，以综合单次和多次GVS单独应用以及与其他干预措施联合应用对患有神经系统疾病的成年人平衡能力有效性的关键研究结果。按照PRISMA指南提取神经系统疾病的诊断、样本量、参与者的年龄和性别、GVS参数、姿势评估以及研究结果。采用纽卡斯尔-渥太华量表评估研究质量。
25项研究纳入了该系统评价。GVS在姿势控制方面的临床应用包括帕金森病、双侧前庭病、中风引起的偏瘫、多发性硬化症、进行性核上性麻痹、持续性姿势-感知性头晕和单侧前庭病。GVS能有效改善大多数神经系统疾病中的姿势控制。偏倚风险评估表明，大多数研究的偏倚风险较低。
GVS是一种有前景的辅助疗法，可改善患有神经系统疾病的成年人的姿势控制和平衡能力。未来应开展高质量研究以证实这些结果。
