Ramos-Lemos Gerardo, Rajesh Kavya, Levine Dov, Zhao Yanling, Hohri Yu, O'Donnell Thomas F X, Patel Virendra, Takayama Hiroo, Kurlansky Paul
Division of Cardiothoracic and Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY.
JTCVS Open. 2025 Jan 27;24:472-483. doi: 10.1016/j.xjon.2025.01.012. eCollection 2025 Apr.
This study investigates the relationship between the Distressed Communities Index and long-term mortality in thoracic aortic aneurysm repair.
This single-center retrospective study includes patients who underwent open thoracic aortic aneurysm repair between 2005 and 2021. The Distressed Communities Index served as a metric for socioeconomic status by providing distress scores for each patient's zip code. Patients were placed into the nondistressed group with a score of 50 or less or the distressed group with a score greater than 50. The primary outcome of this study was 10-year mortality. Multivariable Cox regression evaluated factors associated with long-term mortality while accounting for patient demographics and operative characteristics.
Of 1317 patients, 31% (n = 409) comprised the distressed group, which had higher rates of hypertension ( = .002), chronic obstructive pulmonary disease ( = .03), diabetes ( = .008), cerebrovascular disease ( = .04), and chronic kidney disease ( = .04). This group also experienced higher rates of surgical site infection ( = .02), postoperative respiratory failure ( = .006), and longer hospital stays ( < .001), as well as decreased survival probability at 1 year ( < .001) and beyond ( = .03). Multivariable logistic regression revealed that being in the distressed group was independently associated with increased long-term mortality risk (hazard ratio, 1.66; = .005).
Being from a distressed community is associated with worse long-term mortality after thoracic aortic aneurysm repair. Socioeconomic status should be considered in surgical planning to improve patient outcomes and dismantle healthcare disparities.
本研究调查了困境社区指数与胸主动脉瘤修复术后长期死亡率之间的关系。
这项单中心回顾性研究纳入了2005年至2021年间接受开放性胸主动脉瘤修复术的患者。困境社区指数通过为每位患者的邮政编码提供困境分数,作为社会经济地位的衡量指标。患者被分为分数为50或更低的非困境组或分数大于50的困境组。本研究的主要结局是10年死亡率。多变量Cox回归在考虑患者人口统计学和手术特征的同时,评估了与长期死亡率相关的因素。
在1317名患者中,31%(n = 409)为困境组,该组高血压(P = .002)、慢性阻塞性肺疾病(P = .03)、糖尿病(P = .008)、脑血管疾病(P = .04)和慢性肾病(P = .04)的发生率较高。该组手术部位感染(P = .02)、术后呼吸衰竭(P = .006)的发生率也较高,住院时间更长(P < .001),1年及以后的生存概率降低(P < .001)(P = .03)。多变量逻辑回归显示,处于困境组与长期死亡风险增加独立相关(风险比,1.66;P = .005)。
来自困境社区与胸主动脉瘤修复术后较差的长期死亡率相关。在手术规划中应考虑社会经济地位,以改善患者预后并消除医疗保健差距。