Uzun İrfan, Colak Enes, Atlıhan Zeliha, Mutaf Çağrı, Reyhan Ali Hakim, Yüksekyayla Funda
Department of Ophthalmology, Faculty of Medicine, Harran University, 63100 Sanlıurfa, Türkiye.
Department of Pediatry, Faculty of Medicine, Harran University, 63100 Sanlıurfa, Türkiye.
Children (Basel). 2025 Mar 26;12(4):413. doi: 10.3390/children12040413.
: Childhood obesity is a significant health concern also capable of impacting ocular health. This study evaluates the effects of childhood obesity on corneal morphology, anterior chamber parameters, intraocular pressure (IOP), and corneal endothelial cell morphology. Understanding these relationships may contribute to early diagnosis and management strategies. This prospective, cross-sectional study was conducted at the Harran University Faculty of Medicine between January and December, 2024. Ninety children aged 7-17 years were included, with only the right eyes being analyzed. The participants were categorized into three groups based on body mass index (BMI) percentiles: normal weight (≤85th percentile), overweight (86-94th percentiles), and obese (≥95th percentile). All participants underwent comprehensive ophthalmological examinations, including IOP measurement with a non-contact tonometer, corneal topography assessment using a Scheimpflug camera, and endothelial cell morphology evaluation via specular microscopy. : IOP was significantly higher in the overweight and obese groups ( < 0.001). Central corneal thickness (CCT) also increased significantly in these groups ( < 0.05). Positive correlations were determined between BMI and IOP (r = 0.493, < 0.001) and CCT (r = 0.345, < 0.001). Additionally, waist circumference exhibited a strong correlation with BMI (r = 0.905, < 0.001) and a significant association with IOP (r = 0.463, < 0.001). No significant differences were observed among the groups in terms of other anterior chamber or endothelial parameters. : Childhood obesity is associated with increased IOP and CCT, suggesting potential alterations in corneal biomechanics and ocular physiology. These findings highlight the importance of routine ophthalmological evaluation in obese children to detect early ocular changes and prevent long-term complications.
儿童肥胖是一个重大的健康问题,也会影响眼部健康。本研究评估儿童肥胖对角膜形态、前房参数、眼压(IOP)和角膜内皮细胞形态的影响。了解这些关系可能有助于早期诊断和管理策略。 这项前瞻性横断面研究于2024年1月至12月在哈兰大学医学院进行。纳入了90名7至17岁的儿童,仅分析右眼。参与者根据体重指数(BMI)百分位数分为三组:正常体重(≤第85百分位数)、超重(第86 - 94百分位数)和肥胖(≥第95百分位数)。所有参与者均接受了全面的眼科检查,包括使用非接触眼压计测量眼压、使用眼前节分析仪进行角膜地形图评估以及通过镜面显微镜评估内皮细胞形态。 超重和肥胖组的眼压显著更高(<0.001)。这些组的中央角膜厚度(CCT)也显著增加(<0.05)。确定BMI与眼压(r = 0.493,<0.001)和CCT(r = 0.345,<0.001)之间存在正相关。此外,腰围与BMI呈现出强相关性(r = 0.905,<0.001),与眼压也存在显著关联(r = 0.463,<0.001)。在其他前房或内皮参数方面,各组之间未观察到显著差异。 儿童肥胖与眼压和CCT升高有关,提示角膜生物力学和眼生理可能发生改变。这些发现凸显了对肥胖儿童进行常规眼科评估以检测早期眼部变化并预防长期并发症的重要性。