Hawkins K L, Diters R W, McGrath J T
J Comp Pathol. 1985 Jul;95(3):469-74. doi: 10.1016/0021-9975(85)90052-0.
Craniopharyngiomas are rare in dogs. A 3 cm suprasellar craniopharyngioma in a 13-month-old male mongrel dog is described. The mass consisted of multiple microcysts and solid areas with mesenchymal proliferation in areas of transition. Tumour cells were arranged in solid sheets or separated into islands by thick bands of collagen. Squamous differentiation of tumour cells with keratin formation and a focus of osseous metaplasia were present. Occasionally, tumour cells were arranged in rosettes. Cysts were lined by a single layer of cuboidal to low columnar epithelium and contained proteinaceous fluid with numerous cholesterol clefts. The diagnosis was based on age of occurrence, location and histological appearance.
颅咽管瘤在犬类中较为罕见。本文描述了一只13个月大的雄性杂种犬，其鞍上有一个3厘米的颅咽管瘤。肿块由多个微囊肿和实性区域组成，在过渡区域有间充质增生。肿瘤细胞呈实性片状排列，或被厚厚的胶原带分隔成岛状。肿瘤细胞有鳞状分化并形成角质，还有一处骨化生灶。偶尔，肿瘤细胞呈玫瑰花结样排列。囊肿内衬单层立方形至低柱状上皮，内含含有大量胆固醇裂隙的蛋白质液体。诊断基于发病年龄、位置和组织学表现。
