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[儿童全胃肠外营养]

[Complete parenteral nutrition in childhood].

作者信息

Berger H, Frisch H, Kofler J, Resch R

出版信息

Infusionsther Klin Ernahr. 1977 Feb;4(1):1-9.

PMID:403131
Abstract

Complete parenteral nutrition by means of continuous intravenous drip into large veins, over a long period, has already shown itself to be of therapeutic use in the field of pediatrics. While the nutritional-physiological aspect of this therapeutic method is clear -- it depends on an accurate and sufficient supply of water, salts, glucose, amino-acids, triglycerides and essential fatty acids, vitamins and trace elements -- in practice it presents difficulties which though often serious are not insurmountable. Especially are to cite the septic complications, which are nearly imperceptible during their development. They are only to accept in view of the often almost hopeless condition of the child, who would be lost without complete parenteral feeding. Similar problems arise through metabolic complications which are caused non rarely only by insufficient dosages and lack of careful supervision but it is generally possible to correct these at an early stage. Complete parenteral nutrition must be exactly indicated. It is indeed a great therapeutic help, particularly when over a longer period -- at least a week or longer -- oral nutrition is impossible or insufficient. Practicall experiences will be reported. A retrospective assessment of 50 cases has shown the tendency (through taking too much care?) to hold the quantity of liquids and supply of calories too short and to administer too much carbohydrates and too little fat.

摘要

通过大静脉长期持续静脉滴注进行完全胃肠外营养,已证明其在儿科领域具有治疗作用。虽然这种治疗方法的营养生理方面是明确的——它依赖于准确且充足地供应水、盐、葡萄糖、氨基酸、甘油三酯和必需脂肪酸、维生素及微量元素——但在实际操作中存在一些困难,尽管这些困难常常很严重,但并非无法克服。尤其值得一提的是感染性并发症,其在发展过程中几乎难以察觉。鉴于患儿常常处于几乎绝望的状态,若没有完全胃肠外营养将会死亡,所以只能接受这些并发症。代谢并发症也会引发类似问题,这些并发症不少时候仅仅是由于剂量不足和缺乏仔细监测导致的,但通常在早期可以纠正这些问题。完全胃肠外营养必须有确切的指征。它确实是一种极大的治疗辅助手段,特别是在较长一段时间内——至少一周或更长时间——口服营养不可能或不充足时。将报告实际经验。对50例病例的回顾性评估显示出一种倾向(可能是过于谨慎?),即液体量和热量供应往往不足,碳水化合物给予过多而脂肪过少。

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