Mor V, Masterson-Allen S, Goldberg R J, Cummings F J, Glicksman A S, Fretwell M D
J Am Geriatr Soc. 1985 Sep;33(9):585-9. doi: 10.1111/j.1532-5415.1985.tb06313.x.
Increases in cancer incidence and mortality reflect the larger numbers of elderly in the population. Using a mortality sample of 1891 biopsy-confirmed cancer patients, analyses reveal older breast, prostate, and cervical-uterine cancer victims were more likely to be diagnosed with metastases. Logistic regression analyses of subsamples of breast (N = 224), lung (N = 513), and colorectal (N = 299) cancer patients indicate that age is significantly inversely related to receipt of both subsequent chemotherapy and radiation therapy, controlling for stage of disease and presence of co-morbid disease. Exceptions to this relationship are the use of radiation therapy among nonmetastatic lung cancer patients and all breast cancer patients. The implications of these findings for current cancer control programs are discussed.
癌症发病率和死亡率的上升反映了人口中老年人口数量的增加。通过对1891例活检确诊的癌症患者的死亡样本进行分析发现，年龄较大的乳腺癌、前列腺癌和子宫颈癌患者更有可能被诊断为已发生转移。对乳腺癌（N = 224）、肺癌（N = 513）和结直肠癌（N = 299）患者子样本的逻辑回归分析表明，在控制疾病分期和并存疾病的情况下，年龄与后续接受化疗和放疗的可能性显著呈负相关。这种关系的例外情况是非转移性肺癌患者和所有乳腺癌患者中放疗的使用情况。文中讨论了这些发现对当前癌症控制项目的影响。
