Wang Wei, Li Chen, Sun Guangsheng, Qiu Cunxi, Mao Zeyu, Wu Zhiyi, Fan Junyi, Jin Yuhan, Liu Kunpeng, Sun Peng, Zhang Lin
Department of Drug Prohibition and Public Security, Criminal Investigation Police University of China, Shenyang, 110035, China.
Key Laboratory of Drug Control Technology in Liaoning Province, Shenyang, 110035, China.
BMC Public Health. 2025 May 2;25(1):1631. doi: 10.1186/s12889-025-22926-7.
Methamphetamine is one of the most abused drugs worldwide. Methamphetamine use disorders (MAUD) not only affect the physical and mental health of addicts but also increase the risk of suicide. Although the suicide rate of MAUD patients is high, there is little research on the clinical characteristics and risk factors of suicide risk in MAUD patients. So, it is necessary to investigate the related risk factors of suicidal ideation of MAUD.
Using response-driven sampling (RDS), a total of 10,225 MAUDs were randomly selected from April to May 2023 in Guangdong, China. MAUD was evaluated by the Beck Scale for Suicide Ideation (BSSI) and divided into a case (n = 1228) and a control group (n = 8997). Multivariate generalized linear mixed model analysis was used to analyze the risk factors of suicidal ideation among MAUDs.
The result of multivariate generalized linear mixed model analysis showed that the dosage of each use of MA (OR = 5.52, 95%CI = 4.93～6.17), age (OR = 1.11, 95%CI = 1.03～1.20), childhood physical abuse(OR = 3.43, 95%CI = 3.17～3.71), childhood emotional neglect(OR = 2.77, 95%CI = 2.60～2.94), introverted and extroverted personality(OR = 2.85, 95%CI = 2.64～3.08), and neurotic personality(OR = 1.15, 95%CI = 1.02～1.30) were the risk factors of suicidal ideation among MAUDs in Guangdong, China.
Suicidal ideation among MAUDs is influenced by family, society, stress, and other factors, so it is necessary to take comprehensive intervention measures.
甲基苯丙胺是全球滥用最为严重的毒品之一。甲基苯丙胺使用障碍（MAUD）不仅影响成瘾者的身心健康，还会增加自杀风险。尽管MAUD患者的自杀率较高，但针对MAUD患者自杀风险的临床特征及危险因素的研究较少。因此，有必要对MAUD患者自杀意念的相关危险因素进行调查。
采用应答驱动抽样（RDS）方法，于2023年4月至5月在中国广东省随机选取10225例MAUD患者。通过贝克自杀意念量表（BSSI）对MAUD进行评估，并分为病例组（n = 1228）和对照组（n = 8997）。采用多变量广义线性混合模型分析MAUD患者自杀意念的危险因素。
多变量广义线性混合模型分析结果显示，每次使用甲基苯丙胺的剂量（OR = 5.52，95%CI = 4.93～6.17）、年龄（OR = 1.11，95%CI = 1.03～1.20）、童年期身体虐待（OR = 3.43，95%CI = 3.17～3.71）、童年期情感忽视（OR = 2.77，95%CI = 2.60～2.94）、内外向性格（OR = 2.85，95%CI = 2.64～3.08）以及神经质人格（OR = 1.15，95%CI = 1.02～1.30）是中国广东省MAUD患者自杀意念的危险因素。
MAUD患者的自杀意念受家庭、社会、压力等多种因素影响，因此有必要采取综合干预措施。
