Ferbert A, Gullotta F
J Neurol. 1985;232(3):134-6. doi: 10.1007/BF00313887.
A retrograde study was performed in 105 patients operated upon between 1950 and 1972 for a cerebellar astrocytoma. Complete histories were available for 89 patients. Forty-five patients died within the first 3 months after operation. Of the 32 patients who were still alive, 14 patients had been operated upon 20-30 years previously and 18 patients 10-19 years previously. Twelve patients died over 3 months after the operation; in 6 cases, recurrence of tumour was the cause of death. Of the 7 patients who were irradiated post-operatively, 5 died. In 26 patients the tumor had infiltrated the brain-stem and only 7 patients survived the operation. However, 2 patients are still alive after 25 and 10 years, respectively. The findings indicate that patients operated upon for a localized cerebellar astrocytoms can be considered cured and irradiation and chemotherapy are not warranted. When the tumour has infiltrated the brain-stem, a survival period of more than 20 years is possible after partial resection.
对1950年至1972年间因小脑星形细胞瘤接受手术的105例患者进行了一项回顾性研究。89例患者有完整的病史。45例患者在术后3个月内死亡。在仍存活的32例患者中，14例患者于20至30年前接受手术，18例患者于10至19年前接受手术。12例患者在术后3个月后死亡；6例患者死于肿瘤复发。在术后接受放疗的7例患者中，5例死亡。26例患者的肿瘤侵犯了脑干，只有7例患者术后存活。然而，分别有2例患者在25年和10年后仍存活。研究结果表明，接受局限性小脑星形细胞瘤手术的患者可被视为治愈，无需放疗和化疗。当肿瘤侵犯脑干时，部分切除术后可能有超过20年的生存期。
