Wang Lulu, Fatemi Mostafa, Alizad Azra
Department of Engineering, Reykjavík University, Reykjavík 101, Iceland; Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, MN, 55902, USA; College of Science, Engineering and Technology, University of South Africa, Midrand, 1686, Gauteng, South Africa.
Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, MN, 55902, USA.
Comput Biol Med. 2025 Jun;192(Pt A):110312. doi: 10.1016/j.compbiomed.2025.110312. Epub 2025 May 3.
Artificial intelligence (AI) is transforming fetal brain imaging by addressing key challenges in diagnostic accuracy, efficiency, and data integration in prenatal care. This review explores AI's application in enhancing fetal brain imaging through ultrasound (US) and magnetic resonance imaging (MRI), with a particular focus on multimodal integration to leverage their complementary strengths. By critically analyzing state-of-the-art AI methodologies, including deep learning frameworks and attention-based architectures, this study highlights significant advancements alongside persistent challenges. Notable barriers include the scarcity of diverse and high-quality datasets, computational inefficiencies, and ethical concerns surrounding data privacy and security. Special attention is given to multimodal approaches that integrate US and MRI, combining the accessibility and real-time imaging of US with the superior soft tissue contrast of MRI to improve diagnostic precision. Furthermore, this review emphasizes the transformative potential of AI in fostering clinical adoption through innovations such as real-time diagnostic tools and human-AI collaboration frameworks. By providing a comprehensive roadmap for future research and implementation, this study underscores AI's potential to redefine fetal imaging practices, enhance diagnostic accuracy, and ultimately improve perinatal care outcomes.
人工智能(AI)正在通过应对产前护理中诊断准确性、效率和数据整合方面的关键挑战,改变胎儿脑成像技术。本综述探讨了AI在通过超声(US)和磁共振成像(MRI)增强胎儿脑成像方面的应用,特别关注多模态整合以利用它们的互补优势。通过批判性地分析包括深度学习框架和基于注意力的架构在内的最先进AI方法,本研究突出了重大进展以及持续存在的挑战。显著障碍包括缺乏多样且高质量的数据集、计算效率低下以及围绕数据隐私和安全的伦理问题。特别关注整合US和MRI的多模态方法,将US的可及性和实时成像与MRI卓越的软组织对比度相结合,以提高诊断精度。此外,本综述强调了AI通过实时诊断工具和人机协作框架等创新在促进临床应用方面的变革潜力。通过为未来研究和实施提供全面路线图,本研究强调了AI重新定义胎儿成像实践、提高诊断准确性并最终改善围产期护理结果的潜力。