Okuda T, Fujita Y, Kajiwara N M, Date C, Miyatani S, Ichikawa M, Miyoshi H, Heywood P F, Alpers M P, Koishi H
J Nutr Sci Vitaminol (Tokyo). 1985 Apr;31(2):197-207. doi: 10.3177/jnsv.31.197.
Hematological values and serum amino-acid concentrations were measured in 17 healthy male adult Papua New Guinea highlanders who live on a sweet-potato staple diet. Hematological values were within the normal range, except for a low serum urea concentration. The concentrations of serum threonine, valine, isoleucine, leucine and tyrosine were significantly lower, and those of arginine, glutamate, glycine and alanine were significantly higher, than in Japanese controls. These amino acid patterns in the serum of Papua New Guinea highlanders are an indication of low protein nutrition and adequate energy supply. Some essential amino acid and urea concentrations in the serum of nine Papua New Guinea subjects fed on an adequate protein diet (1.3 g/kg body weight, about twice their habitual diet) for 13 days were significantly increased but were still significantly lower than those of Japanese subjects. Serum alanine decreased on an adequate protein diet. These results show that amino acid uptake and utilization by peripheral tissues may be accelerated on an adequate protein diet. Blood status and serum amino acid concentrations did not show any change except for urea and some amino acids, when five Papua New Guinea highlanders were fed on a low protein diet (0.6 g/kg) consecutively for 13 days.
对17名以甘薯为主食的健康成年巴布亚新几内亚男性高地人进行了血液学指标和血清氨基酸浓度的测定。除血清尿素浓度较低外，血液学指标均在正常范围内。与日本对照组相比，血清苏氨酸、缬氨酸、异亮氨酸、亮氨酸和酪氨酸的浓度显著降低，而精氨酸、谷氨酸、甘氨酸和丙氨酸的浓度显著升高。巴布亚新几内亚高地人血清中的这些氨基酸模式表明其蛋白质营养水平较低但能量供应充足。9名巴布亚新几内亚受试者以充足蛋白质饮食（1.3克/千克体重，约为其习惯饮食的两倍）喂养13天后，血清中的一些必需氨基酸和尿素浓度显著升高，但仍显著低于日本受试者。充足蛋白质饮食时血清丙氨酸降低。这些结果表明，充足蛋白质饮食时外周组织对氨基酸的摄取和利用可能会加快。当5名巴布亚新几内亚高地人连续13天食用低蛋白饮食（0.6克/千克）时，除尿素和一些氨基酸外，血液状况和血清氨基酸浓度没有任何变化。
