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原发性内镜下泪囊鼻腔造口术置入与未置入硅胶支架的结果比较:一项随机临床试验

Comparison of Results of Primary Endoscopic Dacryocystorhinostomy With and Without Silicon Stent Placement: A Randomized Clinical Trial.

作者信息

Akbari Maryam, Jalali Mir Mohammad, Nasirmohtaram Sevil, Habibi Ali Faghih, Moghadam Reza Soltani, Mazloom Farnaz, Fani Ghaffar

机构信息

Otorhinolaryngology Research Center, Department of Otolaryngology and Head and Neck Surgery, School of Medicine, Amiralmomenin Hospital, Guilan University of Medical Sciences, Rasht, Iran.

Eye Research Center, Eye Department, School of Medicine, Amiralmomenin Hospital, Guilan University of Medical Sciences, Rasht, Iran.

出版信息

Indian J Otolaryngol Head Neck Surg. 2025 May;77(5):2097-2103. doi: 10.1007/s12070-025-05453-0. Epub 2025 Apr 8.

Abstract

Nasolacrimal duct obstruction (NLD) causes continuous epiphora. NLD is mainly treated by dacryocystorhinostomy (DCR). There are different opinions about the use of silicone stents in studies. Some support it, but others do not recommend it due to side effects. This study was done to evaluate and compare the results of endoscopic DCR with and without silicone stenting. In this randomized clinical trial study, a total of 66 patients with NLD obstruction were enrolled and were randomly assigned to two groups: Group A underwent the DCR without silicone stent while Group B underwent the DCR with stent. Two groups were compared in terms of success rate and incidence of complications. twenty-one men and forty- five women participated in this study, and the two groups did not have a statistically significant difference ( = 0.42). The average age in group A was 52.63 ± 12.66 years and in group B was 57.60 ± 14.51 years, which had no significant difference ( = 0.14). The overall success rate after twelve months was 96.8% and 96.7% in groups A and, B respectively. However, there was no significant statistical difference between the two groups ( = 0.98). The incidence of complications in the two groups was low. At 12 months postoperatively, 3 (6.66%) out of 66 patients had complications. The use of silicone stents does not affect the results of endoscopic DCR. Complications and success rates were similar in the two groups, DCR with a stent was not superior to without a stent.

摘要

鼻泪管阻塞(NLD)会导致持续性溢泪。NLD主要通过泪囊鼻腔吻合术(DCR)进行治疗。在研究中,对于硅胶支架的使用存在不同观点。一些人支持使用,而另一些人则因副作用不推荐使用。本研究旨在评估和比较内镜下DCR加用和不加用硅胶支架的效果。在这项随机临床试验研究中,共纳入66例NLD阻塞患者,并随机分为两组:A组接受无硅胶支架的DCR,而B组接受有支架的DCR。比较两组的成功率和并发症发生率。21名男性和45名女性参与了本研究,两组在统计学上无显著差异(P = 0.42)。A组的平均年龄为52.63±12.66岁,B组为57.60±14.51岁,无显著差异(P = 0.14)。12个月后的总体成功率在A组和B组分别为96.8%和96.7%。然而,两组之间无显著统计学差异(P = 0.98)。两组并发症发生率较低。术后12个月时,66例患者中有3例(6.66%)出现并发症。硅胶支架的使用不影响内镜下DCR的效果。两组的并发症和成功率相似,有支架的DCR并不优于无支架的DCR。

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本文引用的文献

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