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韩国认知障碍筛查测试作为痴呆症筛查工具:各分测验得分与韩国版简易精神状态检查表第二版的相关性研究

Cognitive Impairment Screening Test in Korea as a Screening Tool for Dementia: The Correlation Study of Subtest Scores With Korean Version of the Mini Mental State Examination 2nd Edition.

作者信息

Kim Minseong, Heo Doyun, Kim Seonkyeong, Lee Yunjin, Kim Yong Sung, Sung Wonjae, Kim Hee-Jin

机构信息

Department of Neurology, College of Medicine, Hanyang University, Seoul, Korea.

Department of Neurology, Hanyang University Seoul Hospital, College of Medicine, Hanyang University, Seoul, Korea.

出版信息

Dement Neurocogn Disord. 2025 Apr;24(2):126-134. doi: 10.12779/dnd.2025.24.2.126. Epub 2025 Apr 21.

Abstract

BACKGROUND AND PURPOSE

The Cognitive Impairment Screening Test in Korea (CIST-K) was designed to detect cognitive decline. Developed independently and widely used in Korea, it is yet to be validated with other screening tests. This study aimed to introduce normative data to the CIST-K and assess its clinical usefulness through correlation analysis with the Korean version of the Mini-Mental State Examination, 2nd edition (K-MMSE-2).

METHODS

We enrolled 85 participants from a tertiary university hospital in Korea, including patients diagnosed with mild cognitive impairment and Alzheimer's disease by experienced neurologists. Both the CIST-K and K-MMSE-2 were administered to assess the cognitive function of the participants, with scores from each subtest of the neuropsychological tests compared.

RESULTS

Multivariate correlation analysis, which was adjusted for age, sex, and education level, revealed a significant correlation between the two tests in orientation, memory, and attention. However, no significant correlation was found between the two tests in visuospatial and language functions.

CONCLUSIONS

In conclusion, this study demonstrates that some subtests in the CIST-K align with corresponding scores on the K-MMSE-2. However, caution is advised when interpreting visuospatial and language test scores from the CIST-K. Further validity studies are necessary to enhance the sensitivity of each subtest.

摘要

背景与目的

韩国认知障碍筛查测试(CIST-K)旨在检测认知功能衰退。该测试独立开发并在韩国广泛使用,但尚未与其他筛查测试进行验证。本研究旨在引入CIST-K的常模数据,并通过与第二版韩国版简易精神状态检查表(K-MMSE-2)的相关性分析评估其临床实用性。

方法

我们招募了韩国一家三级大学医院的85名参与者,包括经经验丰富的神经科医生诊断为轻度认知障碍和阿尔茨海默病的患者。同时进行CIST-K和K-MMSE-2测试以评估参与者的认知功能,并比较神经心理学测试各子测试的分数。

结果

在对年龄、性别和教育水平进行调整的多变量相关性分析中,发现两项测试在定向、记忆和注意力方面存在显著相关性。然而,在视觉空间和语言功能方面,两项测试之间未发现显著相关性。

结论

总之,本研究表明CIST-K中的一些子测试与K-MMSE-2上的相应分数一致。然而,在解释CIST-K的视觉空间和语言测试分数时应谨慎。需要进一步的效度研究来提高每个子测试的敏感性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba45/12046244/e23413227b95/dnd-24-126-g001.jpg

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