Wright K W, Chrousos G A
J Pediatr Ophthalmol Strabismus. 1985 Jul-Aug;22(4):129-32. doi: 10.3928/0191-3913-19850701-04.
To our knowledge this is the first reported case of cyclopentolate induced bilateral acute angle-closure glaucoma associated with the Weill-Marchesani syndrome without lens subluxation. The diagnosis of Weill-Marchesani syndrome was not initially suspected, and Pilocarpine was used in an attempt to break the acute attack. Treatment with Pilocarpine-induced myosis only worsened the glaucoma by causing a severe pupillary block. This case is important because it demonstrates that mid-dilatation and cycloplegia can induce acute glaucoma in patients with the Weill-Marchesani syndrome and points out the importance for considering the diagnosis of Weill-Marchesani syndrome in any case of acute glaucoma in childhood.
据我们所知，这是首例报道的与韦尔-马歇桑综合征相关的环喷托酯诱发双侧急性闭角型青光眼病例，且无晶状体半脱位。最初并未怀疑韦尔-马歇桑综合征的诊断，曾使用毛果芸香碱试图打破急性发作。毛果芸香碱诱发的瞳孔缩小治疗仅通过引起严重瞳孔阻滞而使青光眼病情恶化。该病例很重要，因为它表明中度散瞳和睫状肌麻痹可在韦尔-马歇桑综合征患者中诱发急性青光眼，并指出在儿童任何急性青光眼病例中考虑韦尔-马歇桑综合征诊断的重要性。
