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法国西部布列塔尼地区的人体囊型棘球蚴病本土病例。

Autochthonous human case of cystic echinococcosis in Brittany, Western part of France.

作者信息

Autier Brice, Baldeyrou Marion, Jeddou Heithem, Barrera Coralie, Gangneux Jean-Pierre

机构信息

Université de Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S, 1085 Rennes, France.

Service de Maladies Infectieuses et Réanimation Médicale, CHU de Rennes, Rennes, France.

出版信息

Food Waterborne Parasitol. 2025 Apr 17;39:e00264. doi: 10.1016/j.fawpar.2025.e00264. eCollection 2025 Jun.

Abstract

Human cystic echinococcosis (CE) is a worldwide infection due to the larval stage of , a taeniid tapeworm of canids. Identification of the causative agent at species level relies on molecular methods such as DNA sequencing or species-specific qPCR, which are rarely used for routine case management. Among the different species within the complex, ( genotype G5 former "cattle strain") has been reported in only 19 human cases worldwide, including 3 in France. We report the 20th case of cystic echinococcosis, which is an French autochthonous case of a patient without usual risk factors for CE, and living in an area not known to be endemic for . This case highlights that medical community should be aware of the benefits from molecular epidemiology in understanding the landscape of parasitic diseases.

摘要

人类囊性棘球蚴病(CE)是一种由犬科动物的带绦虫幼虫阶段引起的全球性感染。在物种水平上鉴定病原体依赖于DNA测序或物种特异性定量PCR等分子方法,这些方法很少用于常规病例管理。在棘球绦虫复合体的不同物种中,奥氏棘球绦虫(基因型G5,原“牛株”)在全球仅19例人类病例中被报道,其中3例在法国。我们报告了第20例奥氏棘球绦虫囊性棘球蚴病病例,这是一例法国本土病例,患者没有CE的常见危险因素,且生活在一个未知为奥氏棘球绦虫地方病流行区的地区。该病例凸显了医学界应意识到分子流行病学在了解寄生虫病流行情况方面的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7337/12049954/f7fc11dd1953/gr1.jpg

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