Dikmen Nur, Özçınar Evren, Kayan Ahmet, Polat Nadir, Eyileten Zeynep, Şırlak Mustafa
Department of Cardiovascular Surgery, Ankara University Faculty of Medicine, Ankara, Türkiye.
Turk Gogus Kalp Damar Cerrahisi Derg. 2024 Dec 31;32(4 Suppl 2):078-79. doi: 10.5606/tgkdc.dergisi.2024.msb-53. eCollection 2024 Nov.
This study aimed to evaluate the efficacy of a nonthermal and nontumescent embolization method using N-butyl cyanoacrylate for managing perforator incompetence.
This single-center retrospective study analyzed 98 consecutive patients diagnosed with perforator vein insufficiency treated with N-butyl cyanoacrylate. The study protocol included physical examinations, Doppler ultrasonography, venous clinical severity scoring, CEAP (Clinical, Etiological, Anatomical, and Pathophysiological) classification, and quality of life assessments before and after the procedure. The primary goal was to compare clinical, functional, and duplex ultrasonography parameters in managing varicose vein diseases with isolated primary perforator incompetence using duplex ultrasonography-guided N-butyl cyanoacrylate treatment. Furthermore, the study evaluated the occlusion rate, procedural pain, phlebitis, ecchymosis, and paresthesia.
The occlusion rate at six months was 96.9%, with a significant reduction in pain and other symptoms of chronic venous insufficiency. The incidence of complications was low. Phlebitis was observed in 3.4% of cases, ecchymosis in 2.8%, and transient paresthesia in 1.7%. There were no reports of severe adverse events, such as deep vein thrombosis or allergic reactions.
Interruption of perforators effectively reduces the symptoms of chronic venous insufficiency and promotes rapid ulcer healing. This nontumescent, nonthermal embolization method can be safely applied with high success rates. The results of this study suggest that N-butyl cyanoacrylate is a viable option for treating perforator incompetence.
本研究旨在评估使用氰基丙烯酸正丁酯的非热、非肿胀栓塞方法治疗穿支功能不全的疗效。
这项单中心回顾性研究分析了98例连续诊断为穿支静脉功能不全并接受氰基丙烯酸正丁酯治疗的患者。研究方案包括体格检查、多普勒超声检查、静脉临床严重程度评分、CEAP（临床、病因、解剖和病理生理）分类以及术前和术后的生活质量评估。主要目标是使用双功超声引导的氰基丙烯酸正丁酯治疗，比较治疗孤立性原发性穿支功能不全的静脉曲张疾病时的临床、功能和双功超声参数。此外，该研究评估了闭塞率、手术疼痛、静脉炎、瘀斑和感觉异常。
六个月时的闭塞率为96.9%，慢性静脉功能不全的疼痛和其他症状显著减轻。并发症发生率较低。静脉炎发生率为3.4%，瘀斑发生率为2.8%，短暂感觉异常发生率为1.7%。未报告严重不良事件，如深静脉血栓形成或过敏反应。
阻断穿支可有效减轻慢性静脉功能不全的症状并促进溃疡快速愈合。这种非肿胀、非热栓塞方法可安全应用且成功率高。本研究结果表明，氰基丙烯酸正丁酯是治疗穿支功能不全的可行选择。
