Pirahanchi Yasaman
Neurology, Swedish Medical Center, Englewood, Colorado, USA.
Case Rep Neurol Med. 2025 Apr 27;2025:3178952. doi: 10.1155/crnm/3178952. eCollection 2025.
We report the case of a 55-year-old right-handed female with a medical history of hypothyroidism and gastric bypass surgery. The patient initially presented with cognitive impairment, dizziness, and unsteady gait. Despite an unremarkable stroke workup, her symptoms progressed rapidly within 2 days, leading to subsequent admissions and a complex diagnostic journey revealing Susac syndrome-a rare autoimmune disorder affecting the brain's microvasculature, retina, and cochlea. The patient's treatment involved aggressive immunosuppression with corticosteroids, IVIG, mycophenolate, and cyclophosphamide. The patient responded well and had progressive improvement, with discharge to home. This case highlights the diagnostic challenges and management strategies for Susac syndrome.
我们报告了一例55岁的右利手女性病例，她有甲状腺功能减退和胃旁路手术病史。患者最初表现为认知障碍、头晕和步态不稳。尽管卒中检查结果无异常，但她的症状在2天内迅速进展，随后多次住院，并经历了复杂的诊断过程，最终确诊为Susac综合征——一种罕见的自身免疫性疾病，影响大脑的微血管、视网膜和耳蜗。患者的治疗包括使用皮质类固醇、静脉注射免疫球蛋白、霉酚酸酯和环磷酰胺进行积极的免疫抑制治疗。患者反应良好，病情逐渐改善，随后出院回家。该病例突出了Susac综合征的诊断挑战和管理策略。
