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通过儿科初级保健小组问诊对青霉素过敏患者进行直接阿莫西林激发试验:一项试点研究。

Direct Amoxicillin Challenges for Penicillin Allergy Through Pediatric Primary Care Group Visits: A Pilot Study.

作者信息

Chow Timothy G, Mercadel Candice, Alvarez Kristin S, Kellam Madeline, Khan David A, Termulo Cesar

机构信息

Division of Allergy and Immunology, Departments of Pediatrics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Center of Innovation and Value at Parkland, Parkland Health, Dallas, Texas, USA.

出版信息

Open Forum Infect Dis. 2025 Apr 24;12(5):ofaf236. doi: 10.1093/ofid/ofaf236. eCollection 2025 May.

Abstract

Novel strategies are needed to expand equitable access to penicillin allergy testing. We performed a pilot study of penicillin allergy testing through direct challenges performed at pediatric primary care group office visits. Ninety-five percent of subjects were delabeled with no severe reactions noted, providing conceptual basis for further implementation studies.

摘要

需要新的策略来扩大青霉素过敏检测的公平可及性。我们通过在儿科初级保健组办公室就诊时进行直接激发试验,开展了一项青霉素过敏检测的试点研究。95%的受试者被去除过敏标签,未观察到严重反应,为进一步的实施研究提供了概念基础。

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本文引用的文献

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Impact of Penicillin Allergy Label on Clinical Outcomes of Pneumonia in Children.青霉素过敏标签对儿童肺炎临床结局的影响。
J Allergy Clin Immunol Pract. 2023 Jun;11(6):1899-1906.e2. doi: 10.1016/j.jaip.2023.03.018. Epub 2023 Mar 21.
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Delabeling penicillin allergy in a pediatric primary care clinic.在儿科初级保健诊所消除青霉素过敏标签
Ann Allergy Asthma Immunol. 2023 May;130(5):667-669. doi: 10.1016/j.anai.2023.01.034. Epub 2023 Feb 2.
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Penicillin Allergy Evaluation and Health Equity: A Call to Action.青霉素过敏评估与健康公平:行动呼吁。
J Allergy Clin Immunol Pract. 2023 Feb;11(2):422-428. doi: 10.1016/j.jaip.2022.12.001. Epub 2022 Dec 12.
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Drug allergy: A 2022 practice parameter update.药物过敏:2022年实践参数更新
J Allergy Clin Immunol. 2022 Dec;150(6):1333-1393. doi: 10.1016/j.jaci.2022.08.028. Epub 2022 Sep 17.
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Penicillin Allergy Delabeling: A Multidisciplinary Opportunity.青霉素过敏标签修正:一个多学科的机会。
J Allergy Clin Immunol Pract. 2020 Oct;8(9):2858-2868.e16. doi: 10.1016/j.jaip.2020.04.059.
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Partnering with general pediatricians to delabel penicillin allergies in children.与普通儿科医生合作去除儿童青霉素过敏标签。
Ann Allergy Asthma Immunol. 2020 Jul;125(1):105-107. doi: 10.1016/j.anai.2020.04.001. Epub 2020 Apr 11.

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