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腹横肌平面阻滞与伤口浸润用于减少腹腔镜半结肠切除术后患者自控镇痛需求的比较:一项回顾性病例对照研究

Transversus Abdominis Plane Block vs. Wound Infiltration for the Reduction of Postoperative Patient-Controlled Analgesia Requirements Following Laparoscopic Hemicolectomy: A Retrospective Case-Control Study.

作者信息

Wright Alfie, Leahy Thomas, Chun Charki, Delmas Hannah M, Miller Sam, Shah Pooja

机构信息

Anaesthetics, Southend University Hospital, Southend, GBR.

Data Science, Artanis AI, London, GBR.

出版信息

Cureus. 2025 Apr 4;17(4):e81707. doi: 10.7759/cureus.81707. eCollection 2025 Apr.

Abstract

Introduction Transversus abdominis plane (TAP) blocks and wound infiltration are commonly used regional analgesic techniques in laparoscopic colorectal surgery. However, their comparative efficacy remains uncertain. This study aimed to evaluate whether TAP blocks reduce postoperative morphine consumption and patient-controlled analgesia (PCA) duration compared to wound infiltration following laparoscopic hemicolectomy. Methods We conducted a retrospective case-control study comparing postoperative opioid requirements and PCA duration in patients who received TAP blocks versus wound infiltration for laparoscopic hemicolectomy. Landmark vs ultrasound-guided TAP block techniques were also compared. The primary outcome was total postoperative morphine consumption via PCA, and the secondary outcome was PCA duration. Data on postoperative adjunct analgesia and patient demographics were also collected. Results Comparing TAP blocks (n=59) and wound infiltration (n=33), no significant difference was found between groups in postoperative morphine consumption via PCA (p=0.111), PCA duration (p=0.092), or average daily morphine requirement via PCA (p=0.452). Comparing ultrasound-guided (n=21) and landmark (n=38) TAP block techniques also yielded no significant difference between groups for each of these dependent variables. Variability in opioid use was high, with large standard deviations observed in all groups. Discussion TAP blocks did not demonstrate a significant opioid-sparing effect compared to wound infiltration following laparoscopic hemicolectomy. These findings contribute to a growing body of literature with conflicting evidence on the efficacy of TAP blocks. However, TAP blocks may offer benefits beyond postoperative opioid-sparing effects. Further prospective studies incorporating postoperative pain scores and recovery metrics are needed to determine their clinical utility in multimodal analgesia protocols for colorectal surgery.

摘要

引言

腹横肌平面(TAP)阻滞和伤口浸润是腹腔镜结直肠手术中常用的区域镇痛技术。然而,它们的相对疗效仍不确定。本研究旨在评估与腹腔镜半结肠切除术后伤口浸润相比,TAP阻滞是否能减少术后吗啡用量和患者自控镇痛(PCA)时间。

方法

我们进行了一项回顾性病例对照研究,比较接受TAP阻滞与伤口浸润的腹腔镜半结肠切除术患者的术后阿片类药物需求量和PCA时间。还比较了 landmark 法与超声引导下TAP阻滞技术。主要结局是术后通过PCA的吗啡总用量,次要结局是PCA时间。还收集了术后辅助镇痛和患者人口统计学数据。

结果

比较TAP阻滞组(n = 59)和伤口浸润组(n = 33),两组在术后通过PCA的吗啡用量(p = 0.111)、PCA时间(p = 0.092)或通过PCA的每日平均吗啡需求量(p = 0.452)方面均未发现显著差异。比较超声引导组(n = 21)和 landmark 法组(n = 38)的TAP阻滞技术,这些因变量在两组之间也未显示出显著差异。阿片类药物使用的变异性很高,所有组的标准差都很大。

讨论

与腹腔镜半结肠切除术后伤口浸润相比,TAP阻滞未显示出显著的阿片类药物节省效应。这些发现为关于TAP阻滞疗效的相互矛盾的证据增添了越来越多的文献。然而,TAP阻滞可能具有术后阿片类药物节省效应之外的益处。需要进一步纳入术后疼痛评分和恢复指标的前瞻性研究,以确定其在结直肠手术多模式镇痛方案中的临床效用。

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