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消化不良患者的内镜检查结果:伊朗东北部马什哈德的一项基于人群的研究。

Endoscopic Findings in Patients Presenting Dyspepsia: A Population-Based Study in Mashhad, North East of Iran.

作者信息

AkbariRad Mina, Firoozi Abdollah, Moodi Ghalibaf AmirAli, Mehrad-Majd Hassan, Kangi Bahram, Beheshti Namdar Ali

机构信息

Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Student Research Committee, Birjand University of Medical Sciences, Birjand, Iran.

出版信息

Middle East J Dig Dis. 2025 Jan;17(1):5-11. doi: 10.34172/mejdd.2025.402. Epub 2025 Jan 31.

DOI:10.34172/mejdd.2025.402
PMID:40322574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12048829/
Abstract

BACKGROUND

The present study aimed to evaluate the endoscopic findings of patients with dyspepsia in Ghaem Hospital, Mashhad, Iran.

METHODS

This cross-sectional study collected endoscopic findings in patients with dyspepsia, including epigastric pain or heartburn, postprandial fullness, and early satiety from Ghaem Hospital from 2019 to 2020.

RESULTS

Totally, 743 patients were studied, and 42.3% (n=314) were male. The mean age was 46 years. Among participants, 85.6% (n=636) were included in the functional dyspepsia group, and the rest were included in the organic dyspepsia group. In the organic dyspepsia group, the highest frequency was related to peptic ulcer disease, with 7.2% (n=53). Moreover, the most common complaint was epigastric pain and heartburn. No significant association was found between comorbidities (=0.083), smoking, and sex (=0.532) with the risk of organic dyspepsia.

CONCLUSION

Dyspepsia is not necessarily accompanied by other comorbidities. The most mentioned chief complaint was epigastric pain or heartburn. Functional dyspepsia was the most common diagnosis in patients with dyspepsia, and the peptic ulcer was the leading cause of organic dyspepsia. There was no difference in the underlying cause of dyspepsia in the sexes.

摘要

背景

本研究旨在评估伊朗马什哈德加姆医院消化不良患者的内镜检查结果。

方法

这项横断面研究收集了2019年至2020年期间加姆医院消化不良患者的内镜检查结果,这些患者包括上腹部疼痛或烧心、餐后饱胀和早饱感。

结果

总共对743例患者进行了研究,其中42.3%(n = 314)为男性。平均年龄为46岁。在参与者中,85.6%(n = 636)被纳入功能性消化不良组,其余被纳入器质性消化不良组。在器质性消化不良组中,最高发病率与消化性溃疡病相关,为7.2%(n = 53)。此外,最常见的症状是上腹部疼痛和烧心。未发现合并症(P = 0.083)、吸烟和性别(P = 0.532)与器质性消化不良风险之间存在显著关联。

结论

消化不良不一定伴有其他合并症。最常提及的主要症状是上腹部疼痛或烧心。功能性消化不良是消化不良患者最常见的诊断,消化性溃疡是器质性消化不良的主要原因。消化不良的潜在原因在性别上没有差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0e3/12048829/2ecda8b3052b/mejdd-17-5-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0e3/12048829/900908d8e49b/mejdd-17-5-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0e3/12048829/2ecda8b3052b/mejdd-17-5-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0e3/12048829/900908d8e49b/mejdd-17-5-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0e3/12048829/2ecda8b3052b/mejdd-17-5-g002.jpg

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本文引用的文献

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What is the Prevalence of Clinically Significant Endoscopic Findings in Subjects With Dyspepsia? Updated Systematic Review and Meta-analysis.消化不良患者中具有临床意义的内镜检查结果的患病率是多少?更新的系统评价和荟萃分析。
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Do Low-Risk Patients With Dyspepsia Need a Gastroscopy? Use of Gastroscopy for Otherwise Healthy Patients With Dyspepsia.消化不良的低风险患者需要做胃镜检查吗?对其他方面健康的消化不良患者进行胃镜检查的情况
J Can Assoc Gastroenterol. 2021 Jul 5;5(1):32-38. doi: 10.1093/jcag/gwab017. eCollection 2022 Feb.
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Value of age and alarm features for predicting upper gastrointestinal malignancy in patients with dyspepsia: an endoscopic database review of 4664 patients in Thailand.
年龄和报警特征对上消化道恶性肿瘤预测价值:泰国 4664 例消化不良患者内镜数据库回顾。
BMJ Open. 2021 Oct 27;11(10):e052522. doi: 10.1136/bmjopen-2021-052522.
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Prevalence of Dyspepsia in Iran: A Systematic Review and Meta-analysis.伊朗消化不良的患病率:一项系统评价与荟萃分析
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Endoscopic Findings in Patients With Uninvestigated Dyspepsia: A Retrospective Study From Qatar.未经调查的消化不良患者的内镜检查结果:卡塔尔的一项回顾性研究。
Cureus. 2020 Oct 26;12(10):e11166. doi: 10.7759/cureus.11166.
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