Xiu Ying-Ling, Lv Bing-Qing
Department of Gynecology and Obstetrics, Fujian Maternal and Child Health Hospital, Fuzhou, Fujian Province, 350000, People's Republic of China.
Int J Womens Health. 2025 Apr 30;17:1183-1191. doi: 10.2147/IJWH.S507648. eCollection 2025.
This study aimed to identify factors influencing the success of a trial of labor after cesarean section (TOLAC) and to evaluate associated maternal and neonatal outcomes.
A retrospective analysis was conducted on data from women with a prior cesarean section who underwent TOLAC at Fujian Maternity and Child Health Hospital in Southeast China between January 2016 and January 2018. Of the 1179 women who attempted TOLAC, 1038 achieved vaginal birth after cesarean (VBAC) while 141 experienced unsuccessful trials. Sociodemographic and clinical characteristics were compared between the successful and unsuccessful TOLAC groups using the -test for normally distributed data, non-parametric tests for non-normally distributed data, and the χ2 test, corrected chi-square test, or Fisher's exact test for categorical variables, as appropriate. Logistic regression analysis was performed to identify factors independently associated with successful TOLAC, with the results expressed as Odds Ratios (ORs) and corresponding 95% Confidence Intervals (CIs).
Multivariable logistic regression analysis revealed that maternal height (OR = 1.09, 95% CI = 1.05-1.14), abdominal circumference (OR = 0.95, 95% CI = 0.91-0.98), ultrasound-estimated fetal weight (OR = 0.99, 95% CI = 0.99-1.00), and history of vaginal delivery (OR = 9.62, 95% CI = 2.33-39.67) were independently associated with successful TOLAC. No significant differences were observed between the successful and unsuccessful TOLAC groups in terms of neonatal asphyxia, postpartum hemorrhage, placental abruption, or bladder injury.
Maternal height, abdominal circumference, ultrasound-estimated fetal weight, and history of vaginal delivery were identified as influential factors for VBAC success. Clinical evaluation of these factors may enhance the selection criteria for TOLAC candidates, potentially increasing VBAC rates and reducing cesarean section rates overall.
本研究旨在确定影响剖宫产术后阴道试产(TOLAC)成功的因素,并评估相关的母婴结局。
对2016年1月至2018年1月在中国东南部福建妇幼保健院接受TOLAC的有剖宫产史的女性数据进行回顾性分析。在1179名尝试TOLAC的女性中,1038名实现了剖宫产术后阴道分娩(VBAC),而141名试产失败。成功和失败的TOLAC组之间的社会人口统计学和临床特征,对于正态分布数据使用t检验,对于非正态分布数据使用非参数检验,对于分类变量则根据情况使用χ2检验、校正卡方检验或Fisher精确检验进行比较。进行逻辑回归分析以确定与成功TOLAC独立相关的因素,结果以优势比(OR)和相应的95%置信区间(CI)表示。
多变量逻辑回归分析显示,产妇身高(OR = 1.09,95% CI = 1.05 - 1.14)、腹围(OR = 0.95,95% CI = 0.91 - 0.98)、超声估计胎儿体重(OR = 0.99,95% CI = 0.99 - 1.00)和阴道分娩史(OR = 9.62,95% CI = 2.33 - 39.67)与成功的TOLAC独立相关。在新生儿窒息、产后出血、胎盘早剥或膀胱损伤方面,成功和失败的TOLAC组之间未观察到显著差异。
产妇身高、腹围、超声估计胎儿体重和阴道分娩史被确定为VBAC成功的影响因素。对这些因素进行临床评估可能会改进TOLAC候选者的选择标准,有可能提高VBAC率并总体降低剖宫产率。