Mirzaaghayan Mohammadreza, Vahdati Zahra, Nematian Hossein, Memarian Sara, Heidari Morteza, Askari Mohammad Hossein, Gharib Behdad
Department of General Surgery, School of Medicine, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
J Tehran Heart Cent. 2024 Apr;19(2):124-131. doi: 10.18502/jthc.v19i2.16202.
This study aimed to determine postoperative cardiac and noncardiac complications and their association with the use of cardiopulmonary bypass (CPB), surgical outcomes (length of hospital and ICU stays), dependence on mechanical ventilation, and mortality.
This retrospective cross-sectional study was conducted on pediatric patients aged 0 to 18 who underwent open or closed cardiac surgery over a 1-year period. The use of CPB support, CPB duration, cardiac surgery complexity according to the risk-adjusted classification for congenital heart surgery (RACHS-1), and demographics were examined as potential risk factors associated with an increased number of postoperative complications. The study was performed at the Children's Medical Center, a teaching hospital affiliated with Tehran University of Medical Sciences in Iran.
A total of 283 surgeries were included in our study. Seventy-six (26.9%) of the study population experienced at least 1 complication. Our analysis revealed that increased CPB durations were associated with higher odds of cardiac complications, with an odds ratio of 1.02 (P=0.002). Moreover, higher RACHS-1 levels were significantly associated with greater numbers of cardiac and noncardiac complications. Additionally, prolonged mechanical ventilation and open-heart surgery intensive care unit (OH-ICU) stays were significantly associated with cardiac and noncardiac complications. Our logistic regression analysis found no association between demographic and clinical risk factors, the number of complications, and mortality.
Postoperative complications occurred in 27% of pediatric heart surgeries. Prolonged mechanical ventilation and OH-ICU stays were significantly associated with cardiac and noncardiac complications. However, no significant association was found between postoperative complications and mortality.
本研究旨在确定术后心脏和非心脏并发症及其与体外循环(CPB)使用、手术结果(住院时间和重症监护病房停留时间)、机械通气依赖程度和死亡率之间的关联。
本回顾性横断面研究针对年龄在0至18岁之间、在1年期间接受开胸或闭式心脏手术的儿科患者进行。CPB支持的使用、CPB持续时间、根据先天性心脏病手术风险调整分类(RACHS-1)的心脏手术复杂性以及人口统计学特征被作为与术后并发症数量增加相关的潜在风险因素进行研究。该研究在伊朗德黑兰医科大学附属教学医院儿童医学中心进行。
我们的研究共纳入283例手术。研究人群中有76例(26.9%)至少经历了1种并发症。我们的分析显示,CPB持续时间增加与心脏并发症的较高几率相关,比值比为1.02(P=0.002)。此外,较高的RACHS-1水平与更多的心脏和非心脏并发症显著相关。另外,机械通气时间延长和心脏直视手术重症监护病房(OH-ICU)停留时间延长与心脏和非心脏并发症显著相关。我们的逻辑回归分析发现人口统计学和临床风险因素、并发症数量与死亡率之间无关联。
27%的儿科心脏手术发生术后并发症。机械通气时间延长和OH-ICU停留时间延长与心脏和非心脏并发症显著相关。然而,术后并发症与死亡率之间未发现显著关联。