Terao T, Miyoshi M, Yoshioka T, Nakano S
Nihon Seirigaku Zasshi. 1985;47(3):130-40.
We first supplied the rats with sucrose which accelerates the synthesis of the very low density lipoprotein (VLDL). After 5 weeks ingestion, we investigated the effects of the long-term endurance exercise on the concentration of the endogenous cholesterol and on the accumulation of the cholesterol ester on the arterial wall, with the emphasis on lipid metabolism, especially on lipoprotein metabolism. The concentrations of triglyceride and VLDL in sucrose-ingested group were significantly higher than control. As to the aortic wall, the total amount of cholesterol ester was increased (almost twice). Regular endurance exercise over long period after serum and hepatic lipids had already reached a high level did not reduced the triglyceride in the liver but in serum. It showed be emphasized that the exercise reduces triglyceride and VLDL-cholesterol, and to this extent does contribute to alleviation of hyperlipidemia and to prevention or moderation of arteriosclerosis.
我们首先给大鼠喂食蔗糖，蔗糖会加速极低密度脂蛋白（VLDL）的合成。在摄入5周后，我们研究了长期耐力运动对内源性胆固醇浓度以及动脉壁上胆固醇酯积累的影响，重点是脂质代谢，尤其是脂蛋白代谢。蔗糖摄入组的甘油三酯和VLDL浓度显著高于对照组。至于主动脉壁，胆固醇酯的总量增加了（几乎翻倍）。在血清和肝脏脂质已经达到高水平后进行长期定期耐力运动，并没有降低肝脏中的甘油三酯，而是降低了血清中的甘油三酯。需要强调的是，运动可降低甘油三酯和VLDL胆固醇，在一定程度上有助于缓解高脂血症以及预防或减轻动脉硬化。
