Murayama N
Nihon Seirigaku Zasshi. 1985;47(4):182-9.
The relationship between 10 components of somatosensory evoked potentials (EPs) and pain discrimination in man was studied using Signal Detection Theory (SDT) psychophysics. Two painful electrical stimuli were delivered to the right index finger in random order over all trials. EPs were recorded from the scalp at the contralateral primary somatic projection area while subjects performed SDT discrimination. The stimulus-response combination was classified into 4 categories according to SDT response: hits, misses, false alarms (FAs) and correct rejections (CRs). The amplitudes and peak latencies of EPs in 4 categories were compared with each other. EPs associated with hits and FAs had significantly greater amplitude at P 190, N 220 and P 270 than those associated with misses and CRs, while there was no change in the amplitude of other components. The amplitude of these 3 components systematically increased with an increase in the magnitude of subjective response. Peak latencies of all components were not related to the response categories. These results indicate that the amplitude of the 3 last components may be concerned with the pain evaluating system in the brain.
利用信号检测理论（SDT）心理物理学研究了体感诱发电位（EPs）的10个成分与人的疼痛辨别之间的关系。在所有试验中，以随机顺序向右手食指施加两种疼痛性电刺激。当受试者进行SDT辨别时，在对侧初级躯体投射区的头皮记录EPs。根据SDT反应，刺激-反应组合分为4类：击中、漏报、误报（FAs）和正确拒斥（CRs）。比较了4类中EPs的振幅和峰潜伏期。与击中及误报相关的EPs在P190、N220和P270处的振幅显著大于与漏报和正确拒斥相关的EPs，而其他成分的振幅没有变化。这3个成分的振幅随着主观反应强度的增加而系统性增加。所有成分的峰潜伏期与反应类别无关。这些结果表明，最后3个成分的振幅可能与大脑中的疼痛评估系统有关。
