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重新审视魏尔啸淋巴结:通过三级医疗医院的细针穿刺细胞学检查探索锁骨上淋巴结的诊断范围

Revisiting Virchow`s Node: Exploring the Diagnostic Spectrum of the Supraclavicular Lymph Node Through Fine-Needle Aspiration Cytology in a Tertiary Care Hospital.

作者信息

Qayoom Sumaira, Shabbir Nida, Sagar Mala, Jaiswal Riddhi, Akhtar Naseem, Kumar Madhu

机构信息

Department of Pathology, King George Medical University, UTTAR PRADESH, INDIA.

Department of Surgical Oncology, King George Medical University, UTTAR PRADESH, INDIA.

出版信息

Turk Patoloji Derg. 2025;1(1):59-64. doi: 10.5146/tjpath.2025.13817.

Abstract

OBJECTIVE

Virchows node, described in 1848, represents a metastasis to the left supraclavicular lymph node, commonly arising from gastric cancer. However, in regions with lower gastric cancer incidence, the relevance of Virchows node and the spectrum of diagnosis associated with supraclavicular lymphadenopathy (SCLAP) needs reevaluation. This study aimed to analyze the spectrum of fine-needle aspiration cytology (FNAC) at a tertiary care institute.

MATERIAL AND METHODS

We retrospectively reviewed all supraclavicular lymph node aspirations performed between March 2019 and August 2022. Data were collected from the Department of Pathology`s electronic records and descriptive analyses were performed.

RESULTS

Out of 270 FNAC procedures for SCLAP, 50 were non-diagnostic. Of the 220 patients, cytological diagnosis was categorized as metastatic malignancy in 120 (54.5%) patients, granulomatous lymphadenitis in 57 (25.9%), reactive lymphadenitis in 11 (5.0%), acute suppurative lymphadenitis in 21 (9.5%), and lymphoproliferative disorder in 10 (4.54%) patients. Among the 120 metastatic cases, the most common type was adenocarcinoma (58.3%). The most common primary site was the lung (22.5%), oral cavity (19.2%), breast (12.5%), and gallbladder (10%). Primary gut carcinomas constitute only 9% of supraclavicular lymph node metastases.

CONCLUSION

The findings suggest a need to reconsider the clinical significance of Virchow`s node, especially in regions with different cancer epidemiology. FNAC remains a critical diagnostic tool in evaluating SCLAP.

摘要

目的

1848年描述的魏尔啸淋巴结代表左锁骨上淋巴结转移,通常由胃癌引起。然而,在胃癌发病率较低的地区,魏尔啸淋巴结的相关性以及与锁骨上淋巴结肿大(SCLAP)相关的诊断范围需要重新评估。本研究旨在分析一家三级医疗机构的细针穿刺细胞学检查(FNAC)范围。

材料与方法

我们回顾性分析了2019年3月至2022年8月期间所有的锁骨上淋巴结穿刺病例。数据从病理科电子记录中收集并进行描述性分析。

结果

在270例SCLAP的FNAC检查中,50例诊断不明确。在220例患者中,细胞学诊断分类为转移性恶性肿瘤的有120例(54.5%),肉芽肿性淋巴结炎57例(25.9%),反应性淋巴结炎11例(5.0%),急性化脓性淋巴结炎21例(9.5%),淋巴增殖性疾病10例(4.54%)。在120例转移病例中,最常见的类型是腺癌(58.3%)。最常见的原发部位是肺(22.5%)、口腔(19.2%)、乳腺(12.5%)和胆囊(10%)。原发性胃肠道癌仅占锁骨上淋巴结转移的9%。

结论

研究结果表明需要重新考虑魏尔啸淋巴结的临床意义,尤其是在癌症流行病学不同的地区。FNAC仍然是评估SCLAP的关键诊断工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9959/12206398/11df11bf2cd3/TurkPatolojiDerg-41-13817-g001.jpg

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