[Strategies for mitigating antibiotic resistance in human medicine from the perspective of the Ministry of Health].

Antibiotic resistance (AMR) is increasing worldwide. The complex interrelationships in their development and spread require a bundle of measures and a cross-sectoral approach that considers the One Health approach. The German Antibiotic Resistance Strategy "DART" summarizes the measures for Germany. Building on two predecessor strategies, "DART 2030," which was adopted in 2023, describes the strategic goals to be achieved during its term. It is supplemented by an action plan published in May 2024, which contains specific activities in the six fields of action: prevention, surveillance and monitoring, appropriate use of antibiotics including laboratory diagnostics, communication and cooperation, European and international cooperation, and research and development. Important actions in human medicine include ensuring the availability of recommendations/guidelines on infection prevention and on the diagnosis and treatment of infections, particularly those in which resistance plays a role. The development of expertise in infectiology will be supported and the surveillance of resistance and antibiotic consumption strengthened across all sectors. Proven exchange formats will be continued in order to improve communication within and between sectors. The population's knowledge about infections, their treatment, and the appropriate use of antibiotics will be strengthened.The action plan will be regularly reviewed and updated. This will be linked to reporting, which will also address progress in achieving specific targets for human medicine.