Cavallo Kathryn, Brody Fredrick
Department of Surgery, George Washington University Hospital, Washington, District of Columbia, USA.
Department of Surgery, Washington DC VA Medical Center, Washington, District of Columbia, USA.
J Laparoendosc Adv Surg Tech A. 2025 Jun;35(6):476-481. doi: 10.1089/lap.2024.0352. Epub 2025 May 5.
Renal cell carcinoma (RCC) is the most common renal cancer and constitutes a significant burden of disease. Tumor thrombus is present in approximately 10% of cases at initial diagnosis and impacts the morbidity and mortality of the disease. The primary treatment for RCC involves resection of the tumor. The presence of tumor thrombus, therefore, is not only important for prognosis but also for operative planning. Operative approach, including vascular control and caval closure are important consideration when resecting RCC with inferior vena cava (IVC) tumor thrombus and varies based on the patient presentation, extent of the tumor, and the surgeon's experience. This article presents a patient with RCC with IVC thrombus who ultimately underwent surgical resection with general surgery, vascular surgery, and urology to showcase the multidisciplinary care, surgical considerations, and current management and treatment strategies for RCC with tumor thrombus.
肾细胞癌(RCC)是最常见的肾癌,构成了重大的疾病负担。在初诊时,约10%的病例存在肿瘤血栓,这会影响该疾病的发病率和死亡率。RCC的主要治疗方法是切除肿瘤。因此,肿瘤血栓的存在不仅对预后很重要,而且对手术规划也很重要。当切除伴有下腔静脉(IVC)肿瘤血栓的RCC时,手术方式,包括血管控制和腔静脉闭合是重要的考虑因素,并且会根据患者的表现、肿瘤范围和外科医生的经验而有所不同。本文介绍了一名患有IVC血栓的RCC患者,该患者最终接受了普通外科、血管外科和泌尿外科的手术切除,以展示多学科护理、手术考虑因素以及伴有肿瘤血栓的RCC的当前管理和治疗策略。