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使用细胞外基质补片治疗心脏手术后的胸骨皮肤瘘。

Treatment of Sternocutaneous Fistula Due to Cardiac Surgery Using Extracellular Matrix Patch.

作者信息

Tabaković Zoran, Marinković Milana, Milačić Petar, Mićović Slobodan, Živković Igor

机构信息

Cardiac Surgery Clinic, Institute for Cardiovascular Diseases "Dedinje", Belgrade, Serbia.

Clinic for Burns, Plastic, and Reconstructive Surgery, University Clinical Center of Serbia, Belgrade, Serbia.

出版信息

Braz J Cardiovasc Surg. 2025 May 5;40(4):e20240137. doi: 10.21470/1678-9741-2024-0137.

DOI:10.21470/1678-9741-2024-0137
PMID:40324026
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12052251/
Abstract

The incidence of sternal wound complications, such as dehiscences, infections, and sternocutaneous fistulas, can reach 10%. Sternocutaneous fistulas are extremely rare, and the only definite therapy is surgical repair. Our experience taught us that combining a traditional approach with an extracellular matrix patch might be a step forward in therapy. We described three examples of surgically reconstructing sternocutaneous fistulas with an extracellular matrix patch (ProxiCor®).

摘要

胸骨伤口并发症的发生率,如裂开、感染和胸骨皮肤瘘,可达10%。胸骨皮肤瘘极为罕见,唯一明确的治疗方法是手术修复。我们的经验告诉我们,将传统方法与细胞外基质贴片相结合可能是治疗上的一个进步。我们描述了三个用细胞外基质贴片(ProxiCor®)手术重建胸骨皮肤瘘的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f5f/12052251/d859df121150/bjcvs-40-04-e20240137-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f5f/12052251/922eb9f874e4/bjcvs-40-04-e20240137-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f5f/12052251/11c64dd8e8f8/bjcvs-40-04-e20240137-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f5f/12052251/d859df121150/bjcvs-40-04-e20240137-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f5f/12052251/922eb9f874e4/bjcvs-40-04-e20240137-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f5f/12052251/11c64dd8e8f8/bjcvs-40-04-e20240137-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f5f/12052251/d859df121150/bjcvs-40-04-e20240137-g03.jpg

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本文引用的文献

1
Review on risk factors, classification, and treatment of sternal wound infection.胸骨伤口感染的风险因素、分类和治疗的综述。
J Cardiothorac Surg. 2023 May 19;18(1):184. doi: 10.1186/s13019-023-02228-y.
2
The sternum reconstruction: Present and future perspectives.胸骨重建:现状与未来展望。
Front Oncol. 2022 Oct 28;12:975603. doi: 10.3389/fonc.2022.975603. eCollection 2022.
3
Decellularized Extracellular Matrix Materials for Cardiac Repair and Regeneration.去细胞细胞外基质材料在心脏修复和再生中的应用。
Adv Healthc Mater. 2019 Mar;8(5):e1801217. doi: 10.1002/adhm.201801217. Epub 2019 Feb 4.
4
Use of an Extracellular Matrix Patch for Sternal Wound Dehiscence after Cardiac Surgery in a Neonate.使用细胞外基质补片治疗新生儿心脏手术后胸骨伤口裂开
Tex Heart Inst J. 2018 Jun 1;45(3):176-178. doi: 10.14503/THIJ-17-6239. eCollection 2018 Jun.
5
Sternal wound infections following open heart surgery - a review.心脏直视手术后的胸骨伤口感染——综述
Scand Cardiovasc J. 2016 Oct-Dec;50(5-6):341-348. doi: 10.1080/14017431.2016.1180427. Epub 2016 May 20.
6
Incidence of sternocutaneous fistulas following open heart surgery in a nationwide cohort.全国队列中心脏直视手术后胸骨皮肤瘘的发生率
Scand J Infect Dis. 2012 Aug;44(8):623-5. doi: 10.3109/00365548.2012.669842. Epub 2012 Apr 12.