• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脑深部电刺激术中头皮皮肤并发症的处理:病例说明

Management of cutaneous scalp complications in deep brain stimulation: illustrative cases.

作者信息

Magnant Gabrielle A, Darbin Olivier, McKee Kelsey, Martino Anthony

机构信息

Department of Neurosurgery, University South Alabama, Mobile, Alabama.

Department of Plastic Surgery, University South Alabama, Mobile, Alabama.

出版信息

J Neurosurg Case Lessons. 2025 May 5;9(18). doi: 10.3171/CASE24833.

DOI:10.3171/CASE24833
PMID:40324325
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12051995/
Abstract

BACKGROUND

Scalp complications following deep brain stimulation (DBS) procedures can lead to hardware removal, posing significant clinical and economic challenges. This report describes 3 cases managed with adjacent tissue rearrangement flap and full-thickness skin graft procedures, along with antibiotic therapy.

OBSERVATIONS

Among the 3 cases, 2 patients presented with local infections on initial evaluation. Six months postreconstruction, scalp complications had resolved in 2 patients without interruption to neuromodulation therapy. Of these 2 patients, one had an active infection at the initial presentation.

LESSONS

Contrary to the prevailing assumption that DBS hardware should be removed in the presence of scalp complications associated with active infection, the authors' findings suggest that hardware can sometimes be preserved. With comprehensive management, including empirical antibiotic therapy, the authors observed that alternative approaches to hardware removal could be valuable for patients at risk of losing DBS therapeutic benefits. https://thejns.org/doi/10.3171/CASE24833.

摘要

背景

脑深部电刺激(DBS)手术后的头皮并发症可导致硬件移除,带来重大的临床和经济挑战。本报告描述了3例采用邻近组织重排皮瓣和全厚皮肤移植手术以及抗生素治疗的病例。

观察结果

在这3例病例中,2例患者在初次评估时出现局部感染。重建术后6个月,2例患者的头皮并发症得到解决,神经调节治疗未中断。在这2例患者中,1例在初次就诊时存在活动性感染。

经验教训

与普遍认为在存在与活动性感染相关的头皮并发症时应移除DBS硬件的假设相反,作者的研究结果表明,硬件有时可以保留。通过包括经验性抗生素治疗在内的综合管理,作者观察到,对于有失去DBS治疗益处风险的患者,替代硬件移除的方法可能很有价值。https://thejns.org/doi/10.3171/CASE24833 。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4473/12051995/f343bc4f24d3/CASE24833_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4473/12051995/dcc9b6a79c3c/CASE24833_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4473/12051995/81bd797d540f/CASE24833_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4473/12051995/f343bc4f24d3/CASE24833_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4473/12051995/dcc9b6a79c3c/CASE24833_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4473/12051995/81bd797d540f/CASE24833_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4473/12051995/f343bc4f24d3/CASE24833_figure_3.jpg

相似文献

1
Management of cutaneous scalp complications in deep brain stimulation: illustrative cases.脑深部电刺激术中头皮皮肤并发症的处理:病例说明
J Neurosurg Case Lessons. 2025 May 5;9(18). doi: 10.3171/CASE24833.
2
Surgical Management of Deep Brain Stimulator Scalp Erosion without Hardware Removal.无需移除硬件的脑深部电刺激器头皮侵蚀的手术治疗
Stereotact Funct Neurosurg. 2017;95(6):385-391. doi: 10.1159/000484323. Epub 2017 Dec 13.
3
Is It Possible to Save the Deep Brain Stimulation Hardware when Presenting with Wound Dehiscence or Hardware Infection?出现伤口裂开或硬件感染时,是否可以保留深部脑刺激硬件?
Stereotact Funct Neurosurg. 2021;99(6):496-505. doi: 10.1159/000517299. Epub 2021 Jul 21.
4
Methods of scalp revision for deep brain stimulator hardware: case report.用于深部脑刺激器硬件的头皮修复方法:病例报告
Neurosurgery. 2008 Mar;62(3 Suppl 1):249-50; discussion 250. doi: 10.1227/01.neu.0000317400.38960.bf.
5
Therapeutic Measures for Infections Originating from Scalp Incisions Following Deep Brain Stimulation in Patients with Parkinson's Disease.
World Neurosurg. 2024 Dec;192:e134-e138. doi: 10.1016/j.wneu.2024.09.051. Epub 2024 Sep 13.
6
Lesion-like effect of gliosis secondary to deep brain stimulation electrode infection: illustrative case.深部脑刺激电极感染继发胶质增生的类病变效应:病例说明
J Neurosurg Case Lessons. 2024 Oct 28;8(18). doi: 10.3171/CASE24502.
7
Incidence and Management of Hardware-Related Wound Infections in Spinal Cord, Peripheral Nerve Field, and Deep Brain Stimulation Surgery: A Single-Center Study.脊髓、周围神经区域及脑深部电刺激手术中与硬件相关的伤口感染的发生率及处理:一项单中心研究
Stereotact Funct Neurosurg. 2024;102(1):13-23. doi: 10.1159/000535054. Epub 2023 Dec 5.
8
Saving the Exposed Deep Brain Stimulation Implant: A Comprehensive Review of Implant Extrusion and Reconstructive Options.挽救暴露的脑深部电刺激植入物:植入物挤出及重建方案的全面综述
Ann Plast Surg. 2022 Dec 1;89(6):e21-e30. doi: 10.1097/SAP.0000000000003318.
9
Reducing hardware-related complications of deep brain stimulation.减少深部脑刺激与硬件相关的并发症。
Can J Neurol Sci. 2005 May;32(2):194-200. doi: 10.1017/s0317167100003966.
10
Reconstruction of chronic scalp erosion after deep brain stimulation surgery.慢性脑深部刺激术后头皮侵蚀的重建。
J Plast Reconstr Aesthet Surg. 2021 Aug;74(8):1807-1813. doi: 10.1016/j.bjps.2020.11.045. Epub 2020 Dec 9.

本文引用的文献

1
Trends and disparities in deep brain stimulation utilization in the United States: a Nationwide Inpatient Sample analysis from 1993 to 2017.美国深部脑刺激疗法使用情况的趋势与差异:1993年至2017年全国住院患者样本分析
Lancet Reg Health Am. 2023 Sep 20;26:100599. doi: 10.1016/j.lana.2023.100599. eCollection 2023 Oct.
2
Hardware-Related Skin Erosion in Deep Brain Stimulation for Parkinson's Disease: How Far Can We Go? An Illustrative Case Report.帕金森病深部脑刺激中与硬件相关的皮肤侵蚀:我们能走多远?一例病例报告
Brain Sci. 2022 Dec 15;12(12):1715. doi: 10.3390/brainsci12121715.
3
Saving the Exposed Deep Brain Stimulation Implant: A Comprehensive Review of Implant Extrusion and Reconstructive Options.
挽救暴露的脑深部电刺激植入物:植入物挤出及重建方案的全面综述
Ann Plast Surg. 2022 Dec 1;89(6):e21-e30. doi: 10.1097/SAP.0000000000003318.
4
Reconstruction of chronic scalp erosion after deep brain stimulation surgery.慢性脑深部刺激术后头皮侵蚀的重建。
J Plast Reconstr Aesthet Surg. 2021 Aug;74(8):1807-1813. doi: 10.1016/j.bjps.2020.11.045. Epub 2020 Dec 9.
5
Surgical Management of Deep Brain Stimulator Infection without Electrode Removal: Report of Two Cases.不取出电极的脑深部电刺激器感染的外科治疗:2例报告
J Neurol Surg Rep. 2020 Jan;81(1):e15-e19. doi: 10.1055/s-0039-3399569. Epub 2020 Mar 31.
6
Surgical Management of Deep Brain Stimulator Scalp Erosion without Hardware Removal.无需移除硬件的脑深部电刺激器头皮侵蚀的手术治疗
Stereotact Funct Neurosurg. 2017;95(6):385-391. doi: 10.1159/000484323. Epub 2017 Dec 13.
7
The reconstructive management of hardware-related scalp erosion in deep brain stimulation for Parkinson disease.帕金森病深部脑刺激中与硬件相关的头皮侵蚀的重建处理
Ann Plast Surg. 2014 Sep;73(3):291-4. doi: 10.1097/SAP.0b013e318276da63.
8
Management of device-related wound complications in deep brain stimulation surgery.脑深部电刺激术相关装置并发症的处理。
J Neurosurg. 2012 Jun;116(6):1324-32. doi: 10.3171/2012.1.JNS111798. Epub 2012 Mar 9.
9
Management of skin erosion following deep brain stimulation.脑深部电刺激术后皮肤糜烂的处理
Neurosurg Rev. 2009 Jan;32(1):111-4; discussion 114-5. doi: 10.1007/s10143-008-0158-0. Epub 2008 Sep 5.
10
Hardware-related complications of deep brain stimulation: a review of the published literature.脑深部电刺激的硬件相关并发症:已发表文献综述
Stereotact Funct Neurosurg. 2006;84(5-6):248-51. doi: 10.1159/000096499. Epub 2006 Oct 23.