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门诊部环境下用于处方分析和抗生素监测的数字平台。

Digital platform for prescription analytics and antibiotic surveillance in an outpatient department setup.

作者信息

Kankanala Saumya, Joshi Krishna Prakash, Khan Mohammad Nezamuddin, Dixit Rohit, Gunasekaran Rohini, Gupta Tarun, Gupta Yogendra Kumar

机构信息

Department of General Medicine, SVS Medical College and Hospital, Mahabubnagar, Telangana, India.

Department of Community Medicine, SVS Medical College and Hospital, Mahabubnagar, Telangana, India.

出版信息

Indian J Pharmacol. 2025 Jan 1;57(1):27-32. doi: 10.4103/ijp.ijp_201_25. Epub 2025 May 6.

Abstract

OBJECTIVES

The analysis of prescriptions plays a crucial role in promoting rational drug use, minimizing medication errors, and enabling effective antimicrobial surveillance. Manual analyzing is time-consuming, expensive, and error-prone. This study aimed to evaluate prescribing patterns and antimicrobial surveillance using a novel digital analytical platform in a tertiary care hospital.

METHODOLOGY

A descriptive observational study was conducted in a tertiary care hospital, in India, between June and August 2024. Prescription data were collected from outpatient departments (general medicine, surgery, pediatrics, pulmonology, and orthopedics) and analyzed using the VaidyaRx digital analytic platform. World Health Organization Core Prescribing Indicators were applied to assess prescribing trends, generic drug usage, antibiotic prescribing patterns, fixed-dose combination (FDC), and adherence to the National List of Essential Medicines (NLEM). Data were analyzed using MS Excel and VaidyaRx.

RESULTS

Mean patient age was 35.8 ± 19.2 years, with pediatrics (21.8%), adult (73.3%), and geriatric (4.9%). The average drugs per prescription were 3.2, and generic prescriptions were 37.5%. Antibiotics were prescribed in 24.9% of prescriptions, highest in surgery (46.9%), with ofloxacin + ornidazole and amoxicillin + potassium clavulanate being the most common. NLEM drug use was 36.7%, with more FDCs from non-NLEM (40.9%) than NLEM (8.3%) drugs. Only 64.5% of prescriptions mentioned dosage, raising concerns about completeness.

CONCLUSIONS

Using the VaidyaRx digital platform, real-time prescription analysis was possible which helped in enhancing medication safety and antimicrobial stewardship. Suitable interventions are needed to reduce polypharmacy, increase generic prescribing, ensure rational antibiotic use, and improve prescribing practices.

摘要

目的

处方分析在促进合理用药、减少用药错误以及实现有效的抗菌药物监测方面发挥着关键作用。人工分析既耗时、成本高又容易出错。本研究旨在使用一个新型数字分析平台评估一家三级医院的处方模式和抗菌药物监测情况。

方法

2024年6月至8月在印度一家三级医院开展了一项描述性观察研究。从门诊科室(普通内科、外科、儿科、肺病科和骨科)收集处方数据,并使用VaidyaRx数字分析平台进行分析。应用世界卫生组织核心处方指标来评估处方趋势、通用名药物使用情况、抗生素处方模式、固定剂量复方制剂(FDC)以及对国家基本药物清单(NLEM)的依从性。使用MS Excel和VaidyaRx对数据进行分析。

结果

患者平均年龄为35.8±19.2岁,其中儿科患者占21.8%,成人患者占73.3%,老年患者占4.9%。每张处方的平均用药数量为3.2种,通用名处方占37.5%。24.9%的处方开具了抗生素,外科科室开具抗生素的比例最高(46.9%),最常用的是氧氟沙星+奥硝唑和阿莫西林+克拉维酸钾。NLEM药物的使用率为36.7%,非NLEM药物的FDCs(40.9%)多于NLEM药物(8.3%)。只有64.5%的处方注明了剂量,这引发了对处方完整性的担忧。

结论

使用VaidyaRx数字平台可以进行实时处方分析,这有助于提高用药安全性和抗菌药物管理水平。需要采取适当干预措施以减少联合用药、增加通用名处方开具、确保抗生素合理使用并改善处方习惯。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/038a/12133053/ecae268ec846/IJPharm-57-27-g001.jpg

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