工作年龄人口中的腰痛：来自《2021年全球疾病负担研究》

Low back pain among the working-age population: from the global burden of disease study 2021.

作者信息

Zhang Yao-Kan, Wang Jia-Xuan, Ge Yi-Zhou, Wang Ze-Bin, Chang Feng

机构信息

The Orthopedic Department of Shanxi Provincial People's Hospital, Shanxi Medical University, Taiyuan, 030012, China.

Fifth Clinical Medical College, Shanxi Medical University, Taiyuan, 030012, China.

出版信息

BMC Musculoskelet Disord. 2025 May 5;26(1):441. doi: 10.1186/s12891-025-08704-x.

DOI:10.1186/s12891-025-08704-x

PMID:40325390

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12051354/

Abstract

BACKGROUND

The burden of low back pain in the global working-age population (WAP) is substantial and exhibits unique characteristics. This study aimed to evaluate global, regional, and national trends in low back pain prevalence among the WAP over a 32-year period.

METHODS

We utilized data from the 2021 Global Burden of Disease (GBD) study to evaluate the global impact of low back pain in the WAP from 1990 to 2021. A secondary analysis focused on temporal trends and a decomposition analysis of low back pain.

RESULTS

From 1990 to 2021, there was a continuous decrease in the rate of low back pain among the global WAP. The age-standardized incidence rate (ASIR) decreased from 4,111 (95% uncertainty interval [UI]: 2,682-5,619) to 3,676 (95% UI: 2,563-5,021), with an annual average percentage change (AAPC) of -0.36. The age-standardized prevalence rate (ASPR) decreased from 9,731 (95% UI: 7,061-12,970) to 8,632 (95% UI: 6,296-11,517), with an AAPC of -0.39. The age-standardized disability-adjusted life years (DALYs) rate (ASDR) decreased from 1,108 (95% UI: 686-1,650) to 982 (95% UI: 608-1,460), with an AAPC of -0.39. However, the number of low back pain cases in the global WAP continued to increase. Regions with a middle Socio-demographic Index (SDI), South Asia, China, and India carried a heavier burden of low back pain in the WAP. The burden was also greater among females, with the gender gap continuing to widen. Decomposition analysis revealed that population growth and population aging were the predominant driving factors.

CONCLUSIONS

Despite the overall reduction in the ASIR, ASPR, and ASDR of low back pain among WAP, it remained a leading cause of disability worldwide. More attention needs to be paid to the low back pain burden among WAP in middle-SDI regions, countries with a large population base, and females. Significant gender and regional disparities persist within WAP, highlighting the necessity for targeted preventive and therapeutic interventions to alleviate the burden of low back pain and reduce the risks of disability.

摘要

背景

全球工作年龄人口（WAP）的腰痛负担巨大且具有独特特征。本研究旨在评估32年间WAP中腰痛患病率的全球、区域和国家趋势。

方法

我们利用2021年全球疾病负担（GBD）研究的数据，评估1990年至2021年腰痛对WAP的全球影响。二次分析聚焦于时间趋势以及腰痛的分解分析。

结果

1990年至2021年，全球WAP中腰痛发生率持续下降。年龄标准化发病率（ASIR）从4111（95%不确定区间[UI]：2682 - 5619）降至3676（95% UI：2563 - 5021），年平均百分比变化（AAPC）为 -0.36。年龄标准化患病率（ASPR）从9731（95% UI：7061 - 12970）降至8632（95% UI：6296 - 11517），AAPC为 -0.39。年龄标准化伤残调整生命年（DALYs）率（ASDR）从1108（95% UI：686 - 1650）降至982（95% UI：608 - 1460），AAPC为 -0.39。然而，全球WAP中腰痛病例数持续增加。社会人口指数（SDI）处于中等水平的地区、南亚、中国和印度，在WAP中承担着更重的腰痛负担。女性的负担也更重，性别差距持续扩大。分解分析表明，人口增长和人口老龄化是主要驱动因素。