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机器人辅助根治性前列腺切除术中的侧方入路:在巴西引入加斯顿技术

Lateral Approach in Robotic-Assisted Radical Prostatectomy: Introducing Gaston's Technique in Brazil.

作者信息

Pinto Plinio Ramos, Mourão Thiago Camelo, Nobre Jayme Quirino Caon, Pde Carvalho Rodrigo Coelho, Nunes João Pedro Soares, da Costa Walter Henriques, Gaston Richard Pierre, Zequi Stenio C

机构信息

Departamento de Urologia, AC Camargo Cancer Center, São Paulo, SP, Brasil.

Departamento de Uro-Oncologia Beneficência Portuguesa de São Paulo. São Paulo, SP, Brasil.

出版信息

Int Braz J Urol. 2025 Jul-Aug;51(4). doi: 10.1590/S1677-5538.IBJU.2025.0138.

Abstract

INTRODUCTION

Prostate cancer is one of the most common malignancies in men, significantly impacting quality of life and survival (1, 2). Radical prostatectomy remains a key treatment for localized disease, with ongoing advancements in surgical techniques (3-5). The lateral approach in robotic-assisted prostatectomy was developed by Professor Richard Gaston and has emerged as a method designed to enhance anatomical preservation and functional outcomes, aligning with the growing demand for precision in prostate cancer management (6-8).

OBJECTIVE

To present for the first time in Brazil the step-by-step technique and initial experience with the lateral approach to radical prostatectomy, emphasizing its safety, feasibility, and reproducibility as a novel surgical option for prostate cancer treatment.

MATERIALS AND METHODS

This video demonstrates a lateral approach to radical prostatectomy in a 51-year-old male patient diagnosed with localized prostate cancer (Gleason 7 (3+4) in 2 out of 17 fragments). The surgical procedure was performed using a transperitoneal robotic approach, with lateral entry via the right paravesical space to optimize access and exposure of pelvic structures. Key technical steps included precise dissection of the endopelvic fascia, early identification and preservation of neurovascular bundles, and bladder neck preservation to enhance postoperative functional outcomes. Hemostasis was achieved using selective bipolar energy and clips, and urethrovesical anastomosis was performed using a running suture technique with barbed sutures.

RESULTS

The surgery was performed without complications, with an operative time of 150 minutes and estimated blood loss of 100 mL. The patient was discharged on the first postoperative day with adequate pain control. The urinary catheter was removed on the seventh postoperative day, and the patient reported complete continence from catheter removal onwards, requiring no pads. At three-month follow-up, the patient continued to report full urinary continence and satisfactory erectile function with phosphodiesterase type 5 inhibitors. His PSA levels remained undetectable at 3 and 6 months postoperatively.

CONCLUSIONS

The lateral approach to radical prostatectomy represents a safe and reproducible technique for localized prostate cancer treatment. To our knowledge, this is the first reported case of this approach performed in Brazil, marking an important step in expanding surgical options for prostate cancer. Further studies are required to evaluate long-term clinical outcomes and comparative benefits.

摘要

引言

前列腺癌是男性最常见的恶性肿瘤之一,对生活质量和生存率有重大影响(1,2)。根治性前列腺切除术仍然是局限性疾病的关键治疗方法,手术技术也在不断进步(3-5)。机器人辅助前列腺切除术的外侧入路由理查德·加斯顿教授开发,已成为一种旨在加强解剖结构保留和功能结果的方法,这与前列腺癌管理中对精准度的需求不断增加相契合(6-8)。

目的

首次在巴西展示根治性前列腺切除术外侧入路的分步技术及初步经验,强调其作为前列腺癌治疗新手术选择的安全性、可行性和可重复性。

材料与方法

本视频展示了一名51岁男性患者的根治性前列腺切除术外侧入路,该患者被诊断为局限性前列腺癌(17个切片中有2个切片的 Gleason评分为7(3+4))。手术采用经腹机器人入路,经右侧膀胱旁间隙外侧进入,以优化盆腔结构的显露和暴露。关键技术步骤包括精确解剖盆内筋膜、早期识别和保留神经血管束以及保留膀胱颈以提高术后功能结果。使用选择性双极能量和钛夹实现止血,采用带倒刺缝线的连续缝合技术进行尿道膀胱吻合。

结果

手术无并发症发生,手术时间为150分钟,估计失血量为100毫升。患者术后第一天出院,疼痛得到充分控制。术后第七天拔除导尿管,患者自拔除导尿管后报告完全控尿,无需使用尿垫。在三个月的随访中,患者继续报告完全尿失禁,使用5型磷酸二酯酶抑制剂后勃起功能令人满意。术后3个月和6个月时,他的PSA水平仍无法检测到。

结论

根治性前列腺切除术外侧入路是一种治疗局限性前列腺癌的安全且可重复的技术。据我们所知,这是巴西首次报道的该入路病例,标志着前列腺癌手术选择扩展方面的重要一步。需要进一步研究来评估长期临床结果和比较优势。

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