Mooradian A, Dupont P E, Hlavec A G, Aceto M D, Pearl J
J Med Chem. 1977 Apr;20(4):487-92. doi: 10.1021/jm00214a005.
3-Dimethylamino-1,2,3,4-tetrahydrocarbazole, a structurally modified tryptamine, prevented amphetamine-induced stereotyped behavior in rats and prevented reserpine-induced ptosis in mice. Further study of this compound and a number of substituted derivatives indicated that either imipramine-like or chlorpromazine-like profiles were obtainable by changing substituents and their positions.
3-二甲基氨基-1,2,3,4-四氢咔唑是一种结构修饰的色胺，可预防大鼠中苯丙胺诱导的刻板行为，并预防小鼠中利血平诱导的眼睑下垂。对该化合物及多种取代衍生物的进一步研究表明，通过改变取代基及其位置，可以得到类似丙咪嗪或类似氯丙嗪的特性。
