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高血压远程患者监测项目中临床药师拓展服务及药物滴定的评估

Assessment of clinical pharmacist outreach and medication titration in remote patient monitoring program for hypertension.

作者信息

Shi Helen, Stark Allison, Maity Aloke, Shah Abhishek, Manganelli Joseph, Baichoo Paula, Korchevsky Svetlana, Suthar Pooja, Zhang Chenshu, Rikin Sharon

机构信息

Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.

Department of Medicine, Montefiore Health System, Bronx, NY, USA.

出版信息

J Hum Hypertens. 2025 Jun;39(6):422-424. doi: 10.1038/s41371-025-01025-5. Epub 2025 May 6.

DOI:10.1038/s41371-025-01025-5
PMID:40328888
Abstract

In this implementation science study evaluating the feasibility and effectiveness of a remote patient monitoring program for hypertension, we found that most, but not all of patients received the intended program components of clinical pharmacist outreach and medication titration. Despite feasibility challenges, remote-patient monitoring for hypertension was effective at reducing systolic blood pressure by ≥ 5 mmHg in (64%) and 346 (71%) patients by 3 and 6 months of enrollment respectively. Unexpectedly, chi-square and multivariate logistic regressions analysis showed that the clinical pharmacist outreach, was not associated with blood pressure improvement, but that patient engagement and medication titration were associated with blood pressure improvement. These results suggest that other unmeasured behavioral and lifestyle changes may be a large driver of BP improvement and that while RPM-HTN is a worthwhile intervention, it may not require all ancillary components to deliver meaningful results.

摘要

在这项评估高血压远程患者监测项目可行性和有效性的实施科学研究中,我们发现大多数(但并非所有)患者接受了临床药师随访和药物滴定等预期的项目组成部分。尽管存在可行性挑战,但高血压远程患者监测在入组3个月和6个月时分别使(64%)的患者和346名(71%)的患者收缩压有效降低≥5 mmHg。出乎意料的是,卡方检验和多变量逻辑回归分析表明,临床药师随访与血压改善无关,但患者参与度和药物滴定与血压改善有关。这些结果表明,其他未测量的行为和生活方式改变可能是血压改善的主要驱动因素,虽然高血压远程患者监测是一项有价值的干预措施,但可能并不需要所有辅助组成部分就能产生有意义的结果。

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本文引用的文献

1
Patient Experience in a Remote Patient Monitoring Program for Hypertension: A Qualitative Study.高血压远程患者监测项目中的患者体验:一项定性研究。
Am J Hypertens. 2024 Oct 14;37(11):861-867. doi: 10.1093/ajh/hpae086.
2
Blood pressure outcomes at 12 months in primary care patients prescribed remote physiological monitoring for hypertension: a prospective cohort study.基层医疗患者接受远程生理监测治疗高血压的 12 个月血压结果:一项前瞻性队列研究。
J Hum Hypertens. 2023 Dec;37(12):1091-1097. doi: 10.1038/s41371-023-00850-w. Epub 2023 Jul 21.
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Results of a Remotely Delivered Hypertension and Lipid Program in More Than 10 000 Patients Across a Diverse Health Care Network.
一项通过远程方式提供的高血压和血脂项目在一个多样化的医疗保健网络中的 10000 多名患者中的结果。
JAMA Cardiol. 2023 Jan 1;8(1):12-21. doi: 10.1001/jamacardio.2022.4018.
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Comparing Pharmacist-Led Telehealth Care and Clinic-Based Care for Uncontrolled High Blood Pressure: The Hyperlink 3 Pragmatic Cluster-Randomized Trial.比较药师主导的远程医疗护理和基于诊所的护理对高血压控制不佳的效果:Hyperlink 3 实用集群随机试验。
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J Hypertens. 2017 Jan;35(1):178-187. doi: 10.1097/HJH.0000000000001126.
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Effect of home blood pressure telemonitoring and pharmacist management on blood pressure control: a cluster randomized clinical trial.家庭血压远程监测和药师管理对血压控制的影响:一项集群随机临床试验。
JAMA. 2013 Jul 3;310(1):46-56. doi: 10.1001/jama.2013.6549.