• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

远端指骨骨髓炎的外科治疗:一项叙述性综述。

Surgical management for distal phalanx osteomyelitis: A narrative review.

作者信息

Terrence Jose Jerome J, Kumar Arun, Chandar Dr Mauli

机构信息

European Diploma Hand Surgery, Department of Orthopedics, Hand and Reconstructive Microsurgery, Olympia Hospital & Research Centre, 47, 47A Puthur High Road, Puthur, Trichy, Tamilnadu, 620017, India.

Saveetha Institute of Medical and Technical Sciences, Saveetha Nagar, Thandalam, Kanchipuram Chennai Road, Chennai, Tamilnadu, 602105, India.

出版信息

J Clin Orthop Trauma. 2025 Apr 19;66:103021. doi: 10.1016/j.jcot.2025.103021. eCollection 2025 Jul.

DOI:10.1016/j.jcot.2025.103021
PMID:40329934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12051629/
Abstract

Distal phalanx osteomyelitis, although rare, represents a challenging infection that can have devastating functional and cosmetic consequences if inadequately managed. In patients with comorbidities-most notably diabetes mellitus-the infection may progress rapidly, causing bone destruction, soft tissue involvement, and ultimately, joint destruction. This review discusses the pathophysiology, diagnosis, and surgical management of distal phalanx osteomyelitis. It also highlights key gaps in the current literature, particularly the lack of standardized treatment protocols and limited long-term outcome data, aiming to provide a more consolidated approach to this complex condition. Drawing on current literature and our clinical experience, we outline indications and contraindications for surgery, evaluate imaging modalities and diagnostic criteria, describe detailed surgical techniques (including debridement, dead space management, and reconstruction), and examine the role of antibiotic therapy. We also propose a surgical algorithm based on the extent of infection and review potential complications and outcomes. The article emphasizes that early recognition and aggressive surgical management-coupled with culture-directed antibiotics-are key to optimizing hand function and preventing recurrence.

摘要

远端指骨骨髓炎虽然罕见,但却是一种具有挑战性的感染,如果处理不当,可能会导致严重的功能和外观后果。在患有合并症(最显著的是糖尿病)的患者中,感染可能迅速进展,导致骨质破坏、软组织受累,并最终导致关节破坏。本综述讨论了远端指骨骨髓炎的病理生理学、诊断和手术治疗。它还强调了当前文献中的关键空白,特别是缺乏标准化的治疗方案和有限的长期结果数据,旨在为这种复杂疾病提供一种更综合的治疗方法。借鉴当前文献和我们的临床经验,我们概述了手术的适应症和禁忌症,评估了成像方式和诊断标准,描述了详细的手术技术(包括清创、死腔处理和重建),并研究了抗生素治疗的作用。我们还根据感染程度提出了一种手术算法,并回顾了潜在的并发症和结果。本文强调,早期识别和积极的手术治疗,再加上根据培养结果使用抗生素,是优化手部功能和预防复发的关键。

相似文献

1
Surgical management for distal phalanx osteomyelitis: A narrative review.远端指骨骨髓炎的外科治疗:一项叙述性综述。
J Clin Orthop Trauma. 2025 Apr 19;66:103021. doi: 10.1016/j.jcot.2025.103021. eCollection 2025 Jul.
2
Surgical versus non-surgical interventions for displaced intra-articular calcaneal fractures.手术与非手术干预治疗移位型关节内跟骨骨折。
Cochrane Database Syst Rev. 2023 Nov 7;11(11):CD008628. doi: 10.1002/14651858.CD008628.pub3.
3
Different antibiotic treatments for group A streptococcal pharyngitis.不同的抗生素治疗方案用于治疗 A 组链球菌性咽炎。
Cochrane Database Syst Rev. 2023 Nov 15;11(11):CD004406. doi: 10.1002/14651858.CD004406.pub6.
4
Management of urinary stones by experts in stone disease (ESD 2025).结石病专家对尿路结石的管理(2025年结石病专家共识)
Arch Ital Urol Androl. 2025 Jun 30;97(2):14085. doi: 10.4081/aiua.2025.14085.
5
Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in adults.用于预防成人围手术期意外低温引起并发症的主动体表升温系统。
Cochrane Database Syst Rev. 2016 Apr 21;4(4):CD009016. doi: 10.1002/14651858.CD009016.pub2.
6
Antibiotic treatment for non-tuberculous mycobacteria lung infection in people with cystic fibrosis.囊性纤维化患者非结核分枝杆菌肺部感染的抗生素治疗
Cochrane Database Syst Rev. 2025 Mar 27;3(3):CD016039. doi: 10.1002/14651858.CD016039.
7
Topical antibiotics for preventing surgical site infection in wounds healing by primary intention.用于预防一期愈合伤口手术部位感染的局部用抗生素。
Cochrane Database Syst Rev. 2016 Nov 7;11(11):CD011426. doi: 10.1002/14651858.CD011426.pub2.
8
Rehabilitation for ankle fractures in adults.成人踝关节骨折康复。
Cochrane Database Syst Rev. 2024 Sep 23;9(9):CD005595. doi: 10.1002/14651858.CD005595.pub4.
9
Interventions for improving outcomes in patients with multimorbidity in primary care and community settings.改善基层医疗和社区环境中患有多种疾病患者预后的干预措施。
Cochrane Database Syst Rev. 2016 Mar 14;3(3):CD006560. doi: 10.1002/14651858.CD006560.pub3.
10
Antidepressants for pain management in adults with chronic pain: a network meta-analysis.抗抑郁药治疗成人慢性疼痛的疼痛管理:一项网络荟萃分析。
Health Technol Assess. 2024 Oct;28(62):1-155. doi: 10.3310/MKRT2948.

本文引用的文献

1
Fingertip Injuries Outcome Score.指尖损伤结局评分
Plast Reconstr Surg Glob Open. 2022 Jun 16;10(6):e4386. doi: 10.1097/GOX.0000000000004386. eCollection 2022 Jun.
2
Osteomyelitis of the hand.手部骨髓炎
J Hand Surg Eur Vol. 2016 May;41(4):431-40. doi: 10.1177/1753193415612373. Epub 2015 Oct 19.
3
Trends in the epidemiology of osteomyelitis: a population-based study, 1969 to 2009.骨髓炎流行病学趋势:一项基于人群的研究,1969年至2009年
J Bone Joint Surg Am. 2015 May 20;97(10):837-45. doi: 10.2106/JBJS.N.01350.
4
Acute hand infections.急性手部感染
J Hand Surg Am. 2014 Aug;39(8):1628-35; quiz 1635. doi: 10.1016/j.jhsa.2014.03.031.
5
Management of bone infections in adults: the surgeon's and microbiologist's perspectives.成人骨感染的处理:外科医生和微生物学家的观点。
Injury. 2011 Dec;42 Suppl 5:S18-23. doi: 10.1016/S0020-1383(11)70128-0.
6
Hand infections.手部感染
J Hand Surg Am. 2011 Aug;36(8):1403-12. doi: 10.1016/j.jhsa.2011.05.035.
7
Recurrence of chronic osteomyelitis in a regenerated fibula after 65 years.65年后再生腓骨慢性骨髓炎复发。
Orthopedics. 2007 May;30(5):403-4. doi: 10.3928/01477447-20070501-12.
8
Acro-osteolysis: a complication of Jadassohn-Lewandowsky syndrome.
Int J Dermatol. 2007 Feb;46(2):202-5. doi: 10.1111/j.1365-4632.2006.02935.x.
9
Magnetic resonance imaging for diagnosing foot osteomyelitis: a meta-analysis.磁共振成像诊断足部骨髓炎的Meta分析
Arch Intern Med. 2007 Jan 22;167(2):125-32. doi: 10.1001/archinte.167.2.125.
10
Oral step-down therapy is comparable to intravenous therapy for Staphylococcus aureus osteomyelitis.口服降阶梯疗法治疗金黄色葡萄球菌骨髓炎与静脉治疗效果相当。
J Infect. 2007 Jun;54(6):539-44. doi: 10.1016/j.jinf.2006.11.011. Epub 2007 Jan 2.