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Lengthening of the CHURC1 3' untranslated region by alternative polyadenylation is associated with the progression of acute myeloid leukemia.

作者信息

Hu Xi, Cao Panxiang, Wang Fang, Zhang Huqin, Wang Tong, Liu Hongxing, Wu Xiaoming

机构信息

The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, China.

Division of Pathology and Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, Hebei 065201, China.

出版信息

Genes Dis. 2024 Feb 28;12(1):101248. doi: 10.1016/j.gendis.2024.101248. eCollection 2025 Jan.

DOI:10.1016/j.gendis.2024.101248
PMID:40329942
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12053556/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d0f/12053556/fafc18f021ab/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d0f/12053556/fafc18f021ab/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d0f/12053556/fafc18f021ab/gr1.jpg

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本文引用的文献

1
A Novel apaQTL-SNP for the Modification of Non-Small-Cell Lung Cancer Susceptibility across Histological Subtypes.一种用于改变不同组织学亚型非小细胞肺癌易感性的新型apaQTL-SNP
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2
Alternative polyadenylation dysregulation contributes to the differentiation block of acute myeloid leukemia.可变聚腺苷酸化失调导致急性髓系白血病分化阻滞。
Blood. 2022 Jan 20;139(3):424-438. doi: 10.1182/blood.2020005693.
3
SNP2APA: a database for evaluating effects of genetic variants on alternative polyadenylation in human cancers.
SNP2APA：一个用于评估人类癌症中遗传变异对可变多聚腺苷酸化影响的数据库。
Nucleic Acids Res. 2020 Jan 8;48(D1):D226-D232. doi: 10.1093/nar/gkz793.
4
Alternative cleavage and polyadenylation in health and disease.可变剪接和多聚腺苷酸化在健康和疾病中的作用。
Nat Rev Genet. 2019 Oct;20(10):599-614. doi: 10.1038/s41576-019-0145-z. Epub 2019 Jul 2.
5
Comprehensive Characterization of Alternative Polyadenylation in Human Cancer.全面描绘人类癌症中的可变多聚腺苷酸化。
J Natl Cancer Inst. 2018 Apr 1;110(4):379-389. doi: 10.1093/jnci/djx223.