Musleh Mais, AlMokbel Amani
Department of Hematology, Faculty of Medicine, Damascus University, Damascus, Syria.
Department of Gastroenterology, Faculty of Medicine, Damascus University, Damascus, Syria.
Case Rep Gastrointest Med. 2025 Apr 28;2025:6259846. doi: 10.1155/crgm/6259846. eCollection 2025.
Celiac crisis (CC) is a rare but potentially life-threatening complication of celiac disease (CD), characterized by severe diarrhea, electrolyte imbalances, and metabolic disturbances. We report the case of a 32-year-old pregnant woman presented significant dehydration, weight loss, and steatorrheic stools. Diagnosis was confirmed by duodenal biopsy, with rapid improvement following a gluten-free diet (GFD) and corticosteroids. The diagnosis of CC was established based on the acute clinical presentation and rapid improvement following a GFD and corticosteroid therapy. This case highlights the importance of early recognition and prompt management of CC, particularly in undiagnosed or untreated CD, to prevent severe maternal and fetal complications.
乳糜泻危象（CC）是乳糜泻（CD）一种罕见但可能危及生命的并发症，其特征为严重腹泻、电解质失衡和代谢紊乱。我们报告了一例32岁孕妇，出现明显脱水、体重减轻和脂肪泻。十二指肠活检确诊，采用无麸质饮食（GFD）和皮质类固醇后病情迅速改善。CC的诊断基于急性临床表现以及GFD和皮质类固醇治疗后的快速改善。该病例强调了早期识别和及时处理CC的重要性，尤其是在未诊断或未治疗的CD中，以预防严重的母婴并发症。
