Dabbaghi Mohammad Mahdi, Fadaei Mohammad Saleh, Goldoozian Maral, Fadaei Mohammad Reza, Baradaran Rahimi Vafa, Askari Vahid Reza
Clinical Research Development Unit, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Biochem Biophys Rep. 2025 Apr 22;42:102023. doi: 10.1016/j.bbrep.2025.102023. eCollection 2025 Jun.
Natural toxins produced by various living organisms pose significant risks to health, food security, and environmental balance through inhalation, ingestion, and other exposure routes. This review focuses on the ameliorative effects of different species, which comprise over 130 perennial herbs known for their therapeutic properties. A systematic examination of data from Scopus, PubMed, and Web of Science was conducted, encompassing various studies without date restrictions, ensuring a comprehensive selection of articles based on full-text availability. The results of this study indicate that exhibits anti-hyperglycemic and anti-hyperlipidemic properties, enhances collagen proliferation regulation, suppresses inflammatory responses, and displays significant antioxidant activity. Similarly, has been shown to have hepatoprotective effects, as evidenced by reduced malondialdehyde levels and increased total thiol concentrations. has also been demonstrated to have cardioprotective effects, with a decrease in inflammatory markers and edema levels. The protective benefits of other species within the genus extend to various toxins. This comprehensive review underscores the potential of species as natural remedies for combating toxicities and promoting health.
各种生物产生的天然毒素通过吸入、摄入和其他接触途径对健康、粮食安全和环境平衡构成重大风险。本综述重点关注不同物种的改善作用，这些物种包括130多种以其治疗特性而闻名的多年生草本植物。对Scopus、PubMed和科学网的数据进行了系统审查，涵盖了各种无日期限制的研究，确保根据全文可用性全面挑选文章。本研究结果表明，[物种名称]具有降血糖和降血脂特性，增强胶原增殖调节，抑制炎症反应，并具有显著的抗氧化活性。同样，[物种名称]已被证明具有肝脏保护作用，丙二醛水平降低和总硫醇浓度增加证明了这一点。[物种名称]也被证明具有心脏保护作用，炎症标志物和水肿水平降低。[属名]内其他物种的保护益处扩展到各种毒素。这一全面综述强调了[物种名称]作为对抗毒性和促进健康的天然药物的潜力。
