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甲状腺癌术后患者的用药依从性及其影响因素:一项横断面研究

Medication Adherence and Its Influencing Factors in Postoperative Thyroid Cancer Patients: A Cross-Sectional Study.

作者信息

Li Wen, Yu Luxin, Zheng Hui, Soh Kim Geok, Soh Kim Lam

机构信息

Gastrointestinal Surgery, Yantai Yuhuangding Hospital, Yantai, Shandong, China.

Nursing Department, Yantai Yuhuangding Hospital, Yantai, Shandong, China.

出版信息

Nurs Res Pract. 2025 Apr 28;2025:6943237. doi: 10.1155/nrp/6943237. eCollection 2025.

Abstract

Medication adherence is critical for the recovery of patients after thyroid cancer surgery. Therefore, this study investigated the current medication adherence status in Chinese postoperative thyroid cancer patients and analysed the influencing factors. A cross-sectional descriptive survey of postoperative thyroid cancer patients at a tertiary-level hospital in Shandong Province, China, from January to June 2019 was conducted, and 266 postoperative thyroid cancer patients were included. The patient's medication adherence was assessed with the Chinese version of the Morrissey Medication Adherence Scale, and the related influencing factors were measured with the General Information Questionnaire and the Rational Medication Self-Efficacy Scale. Finally, factors associated with medication adherence were explored using multiple linear regression analysis. The medication adherence for postoperative thyroid cancer patients is at an intermediate level with a score of (6.25 ± 1.57). Patients' rational medication self-efficacy was positively correlated with medication adherence, with a correlation coefficient () of 0.536 ( < 0.001). Multiple linear regression analyses revealed that education level, disease duration and self-efficacy for rational medication use were the main factors affecting medication adherence in postoperative thyroid cancer patients. Improving patients' self-efficacy in rational medication and strengthening patients' health education are important ways to enhance patients' medication adherence.

摘要

药物依从性对甲状腺癌手术后患者的康复至关重要。因此,本研究调查了中国甲状腺癌术后患者目前的药物依从性状况,并分析了影响因素。对2019年1月至6月在中国山东省一家三级医院的甲状腺癌术后患者进行了横断面描述性调查,纳入了266例甲状腺癌术后患者。采用中文版的莫里西药物依从性量表评估患者的药物依从性,并用一般信息问卷和合理用药自我效能量表测量相关影响因素。最后,采用多元线性回归分析探讨与药物依从性相关的因素。甲状腺癌术后患者的药物依从性处于中等水平,得分为(6.25±1.57)。患者的合理用药自我效能与药物依从性呈正相关,相关系数()为0.536(<0.001)。多元线性回归分析显示,教育水平、病程和合理用药自我效能是影响甲状腺癌术后患者药物依从性的主要因素。提高患者合理用药的自我效能和加强患者的健康教育是提高患者药物依从性的重要途径。

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