Xing Diensn G, Mohiuddin Farhan, Bhuiyan Md Shenuarin, Hossain Md Ismail, Al-Yafeai Zaki, Faisal Abu Saleh Mosa, Goeders Nicholas E, Conrad Steven A, Vanchiere John A, Patterson James C, Kevil Christopher G, Bhuiyan Mohammad Alfrad Nobel
Department of Medicine, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, USA.
These authors contributed equally: Diensn G. Xing, Farhan Mohiuddin.
Nat Ment Health. 2024 Aug;2:951-959. doi: 10.1038/s44220-024-00282-6. Epub 2024 Jun 26.
Methamphetamine is a growing health problem, as is mental health illness. However, no studies have investigated the combinatory effects of both diseases or characterized national trends over a period of time greater than 10 years. We evaluated US trends in mental health disorder-related hospital admissions (MHD-HAs) and compared them with those with concurrent methamphetamine use (MHD-HA-MUs), comparing the demographic characteristics from 2008 to 2020. Our findings reveal a significant increase in MHD-HA-MUs, increasing 10.5-fold, compared with a 1.4-fold increase in MHD-HAs. We also found a 1.53 times higher adjusted prevalence ratio of MHD-HA-MUs compared with MHD-HAs, even when adjusted for confounding factors. MHD-HA-MUs increased significantly among male patients (13-fold), non-Hispanic Black patients (39-fold), those aged 41-64 years (16-fold), and the South (24-fold). Overall, the data suggest that there are synergistic effects with methamphetamine use and mental health disorder, highlighting this patient group's unique needs, requiring distinct action.
甲基苯丙胺是一个日益严重的健康问题，心理健康疾病亦是如此。然而，尚无研究调查过这两种疾病的联合影响，也没有对超过10年的全国趋势进行过特征描述。我们评估了美国与心理健康障碍相关的住院人数（MHD-HAs）趋势，并将其与同时使用甲基苯丙胺的患者（MHD-HA-MUs）的趋势进行比较，比较了2008年至2020年的人口统计学特征。我们的研究结果显示，MHD-HA-MUs显著增加，增长了10.5倍，而MHD-HAs仅增长了1.4倍。我们还发现，即使在对混杂因素进行调整后，MHD-HA-MUs的调整患病率比MHD-HAs高1.53倍。MHD-HA-MUs在男性患者（13倍）、非西班牙裔黑人患者（39倍）、41至64岁的患者（16倍）以及南部地区（24倍）中显著增加。总体而言，数据表明甲基苯丙胺使用与心理健康障碍之间存在协同效应，突出了该患者群体的独特需求，需要采取不同的行动。
