Hejazi Seyed Hossein, Kalantari Reza, Mousavi Seyed Mahmoud, Safari Marzieh, Ghayour Zahra, Nokhodian Zary, Esmaeilifallah Mahsa
Department. of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Food Waterborne Parasitol. 2025 Apr 21;39:e00263. doi: 10.1016/j.fawpar.2025.e00263. eCollection 2025 Jun.
is a widespread zoonotic tapeworm that causes human cystic echinococcosis. Human CE, transmitted via dogs or Canidae feces, poses a public health challenge and exemplifies the One Health Theory. This survey was conducted to determine the seroprevalence of CE in individuals occupationally exposed (IOE) to dogs, livestock wool, and contaminated soil due to egg shedding from dogs/Canidae in industrial slaughterhouses and livestock fields, compared to a healthy control group in Isfahan province, central Iran. In a case-control study, 401 sera from IOE, including slaughterhouse workers, animal husbandry unit workers, wool industry workers, farm workers, livestock farmers, butchers, and veterinarians in the case group, were matched with 401 archived samples from the general population. All 802 samples were tested for echinococcosis IgG using ELISA. Out of 802 sera, 7 (0.9 %) tested positive for IgG. The seroprevalence in the IOE and control groups was 1.2 % (5/401) and 0.5 % (2/401), respectively. Although there was a 2.5-fold estimated risk of CE in IOE compared to the control group, this was not statistically significant. Based on the current study's findings, the overall seroprevalence of CE in the Isfahan area is similar to that of other regions in Iran
是一种广泛存在的人畜共患绦虫，可导致人类囊型包虫病。人类囊型包虫病通过狗或犬科动物粪便传播，构成了一项公共卫生挑战，并体现了“同一健康”理论。本调查旨在确定在伊朗中部伊斯法罕省，与健康对照组相比，在工业屠宰场和畜牧场因狗/犬科动物排虫卵而职业暴露于狗、家畜羊毛和受污染土壤的个体中囊型包虫病的血清阳性率。在一项病例对照研究中，将病例组中职业暴露个体（包括屠宰场工人、畜牧单位工人、羊毛行业工人、农场工人、牧民、屠夫和兽医）的401份血清与来自普通人群的401份存档样本进行匹配。使用酶联免疫吸附测定法（ELISA）对所有802份样本进行包虫病IgG检测。在802份血清中，7份（0.9%）IgG检测呈阳性。职业暴露个体组和对照组的血清阳性率分别为1.2%（5/401）和0.5%（2/401）。尽管与对照组相比，职业暴露个体感染囊型包虫病的估计风险高出2.5倍，但这在统计学上并不显著。根据当前研究结果，伊斯法罕地区囊型包虫病的总体血清阳性率与伊朗其他地区相似
